Exploring the mechanism and phytochemicals in Psoraleae Fructus-induced hepatotoxicity based on RNA-seq, in vitro screening and molecular docking
Abstract Psoraleae Fructus (PF) is a widely-used herb with diverse pharmacological activities, while its related hepatic injuries have aroused public concerns. In this work, a systematic approach based on RNA sequencing (RNA-seq), high-content screening (HCS) and molecular docking was developed to i...
Main Authors: | Huiying Shang, Xian Liu, Jinchao Pan, Hongbo Cheng, Zengchun Ma, Chengrong Xiao, Yue Gao |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-50454-0 |
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