Graves’ disease in an adolescent presenting with increased intracranial pressure and bilateral papilledema

Increased intracranial pressure (ICP) can present with symptoms of headache, vomiting, visual changes, and tinnitus. Papilledema may be seen on physical exam. Thyroid disease has been a rare secondary cause of increased ICP. We present a 16-year-old female who had a worsening headache for 6 months....

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Main Authors: Jay Nguyen, Dennis Joseph
Format: Article
Language:English
Published: Bioscientifica 2022-04-01
Series:Endocrinology, Diabetes & Metabolism Case Reports
Online Access:https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM22-0240.xml
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author Jay Nguyen
Dennis Joseph
author_facet Jay Nguyen
Dennis Joseph
author_sort Jay Nguyen
collection DOAJ
description Increased intracranial pressure (ICP) can present with symptoms of headache, vomiting, visual changes, and tinnitus. Papilledema may be seen on physical exam. Thyroid disease has been a rare secondary cause of increased ICP. We present a 16-year-old female who had a worsening headache for 6 months. She was found to have signs, symptoms, physical exam findings, and diagnostic studies consistent with both increased ICP and previously undiagnosed Graves’ disease. The patient was treated with a 19-month course of methimazole 40 mg daily. Her headache and papilledema resolved shortly after medication initiation. The timeline of symptoms and resolution of her increased ICP symptoms with treatment of Graves’ disease suggests that hyperthyroidism was the underlying cause of her increased ICP. Clinicians should consider Graves’ disease as the etiology in pediatric patients presenting with signs and symptoms of increased ICP with papilledema.
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spelling doaj.art-50baa93d602b4022a7b2c9dcfd732a772022-12-22T00:11:19ZengBioscientificaEndocrinology, Diabetes & Metabolism Case Reports2052-05732022-04-01111310.1530/EDM-22-0240Graves’ disease in an adolescent presenting with increased intracranial pressure and bilateral papilledemaJay Nguyen0Dennis Joseph1Lincoln Memorial University-DeBusk College of Osteopathic Medicine, Harrogate, Tennessee, USAEndocrinology Center of Lake Cumberland, Somerset, Kentucky, USAIncreased intracranial pressure (ICP) can present with symptoms of headache, vomiting, visual changes, and tinnitus. Papilledema may be seen on physical exam. Thyroid disease has been a rare secondary cause of increased ICP. We present a 16-year-old female who had a worsening headache for 6 months. She was found to have signs, symptoms, physical exam findings, and diagnostic studies consistent with both increased ICP and previously undiagnosed Graves’ disease. The patient was treated with a 19-month course of methimazole 40 mg daily. Her headache and papilledema resolved shortly after medication initiation. The timeline of symptoms and resolution of her increased ICP symptoms with treatment of Graves’ disease suggests that hyperthyroidism was the underlying cause of her increased ICP. Clinicians should consider Graves’ disease as the etiology in pediatric patients presenting with signs and symptoms of increased ICP with papilledema.https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM22-0240.xml
spellingShingle Jay Nguyen
Dennis Joseph
Graves’ disease in an adolescent presenting with increased intracranial pressure and bilateral papilledema
Endocrinology, Diabetes & Metabolism Case Reports
title Graves’ disease in an adolescent presenting with increased intracranial pressure and bilateral papilledema
title_full Graves’ disease in an adolescent presenting with increased intracranial pressure and bilateral papilledema
title_fullStr Graves’ disease in an adolescent presenting with increased intracranial pressure and bilateral papilledema
title_full_unstemmed Graves’ disease in an adolescent presenting with increased intracranial pressure and bilateral papilledema
title_short Graves’ disease in an adolescent presenting with increased intracranial pressure and bilateral papilledema
title_sort graves disease in an adolescent presenting with increased intracranial pressure and bilateral papilledema
url https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM22-0240.xml
work_keys_str_mv AT jaynguyen gravesdiseaseinanadolescentpresentingwithincreasedintracranialpressureandbilateralpapilledema
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