Phosphatidylserine-Exposing Annexin A1-Positive Extracellular Vesicles: Potential Cancer Biomarkers

Phosphatidylserine-Exposing Annexin A1-Positive Extracellular Vesicles: Potential Cancer Biomarkers

Under physiological conditions, phosphatidylserine (PS) predominantly localizes to the cytosolic leaflet of the plasma membrane of cells. During apoptosis, PS is exposed on the cell surface and serves as an “eat-me” signal for macrophages to prevent releasing self-immunogenic cellular components fro...

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Bibliographic Details
Main Authors: Gloria I. Perez, Matthew P. Bernard, Daniel Vocelle, Ahmed A. Zarea, Najla A. Saleh, Matthew A. Gagea, Doug Schneider, Maxine Bauzon, Terry Hermiston, Masamitsu Kanada
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Vaccines
Subjects:
extracellular vesicle
phosphatidylserine
cancer
biomarker
annexin A1
CD63
Online Access:https://www.mdpi.com/2076-393X/11/3/639

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