On the Need for Human Studies of PM Exposure Activation of the NLRP3 Inflammasome
Particulate matter air pollution is associated with blood inflammatory biomarkers, however, the biological pathways from exposure to periferal inflammation are not well understood. We propose that the NLRP3 inflammasome is likely stimulated by ambient particulate matter, as it is by some other parti...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-02-01
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| Series: | Toxics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2305-6304/11/3/202 |
| _version_ | 1827747477865889792 |
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| author | Doug Brugge Jianghong Li Wig Zamore |
| author_facet | Doug Brugge Jianghong Li Wig Zamore |
| author_sort | Doug Brugge |
| collection | DOAJ |
| description | Particulate matter air pollution is associated with blood inflammatory biomarkers, however, the biological pathways from exposure to periferal inflammation are not well understood. We propose that the NLRP3 inflammasome is likely stimulated by ambient particulate matter, as it is by some other particles and call for more research into this pathway. |
| first_indexed | 2024-03-11T05:49:12Z |
| format | Article |
| id | doaj.art-50c28fb22d0d4157bf2f8b4e27f912eb |
| institution | Directory Open Access Journal |
| issn | 2305-6304 |
| language | English |
| last_indexed | 2024-03-11T05:49:12Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxics |
| spelling | doaj.art-50c28fb22d0d4157bf2f8b4e27f912eb2023-11-17T14:12:33ZengMDPI AGToxics2305-63042023-02-0111320210.3390/toxics11030202On the Need for Human Studies of PM Exposure Activation of the NLRP3 InflammasomeDoug Brugge0Jianghong Li1Wig Zamore2Department of Public Health Sciences, School of Medicine, University of Connecticut, Farmington, CT 06030, USAInstitute for Community Research, Hartford, CT 06106, USASomerville Transportation Equity Partnership, Somerville, MA 02145, USAParticulate matter air pollution is associated with blood inflammatory biomarkers, however, the biological pathways from exposure to periferal inflammation are not well understood. We propose that the NLRP3 inflammasome is likely stimulated by ambient particulate matter, as it is by some other particles and call for more research into this pathway.https://www.mdpi.com/2305-6304/11/3/202particulate matter air pollutionNLRP3 inflammasomeresearch needs |
| spellingShingle | Doug Brugge Jianghong Li Wig Zamore On the Need for Human Studies of PM Exposure Activation of the NLRP3 Inflammasome Toxics particulate matter air pollution NLRP3 inflammasome research needs |
| title | On the Need for Human Studies of PM Exposure Activation of the NLRP3 Inflammasome |
| title_full | On the Need for Human Studies of PM Exposure Activation of the NLRP3 Inflammasome |
| title_fullStr | On the Need for Human Studies of PM Exposure Activation of the NLRP3 Inflammasome |
| title_full_unstemmed | On the Need for Human Studies of PM Exposure Activation of the NLRP3 Inflammasome |
| title_short | On the Need for Human Studies of PM Exposure Activation of the NLRP3 Inflammasome |
| title_sort | on the need for human studies of pm exposure activation of the nlrp3 inflammasome |
| topic | particulate matter air pollution NLRP3 inflammasome research needs |
| url | https://www.mdpi.com/2305-6304/11/3/202 |
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