Antimicrobial peptide thanatin fused endolysin PA90 (Tha-PA90) for the control of Acinetobacter baumannii infection in mouse model

Antimicrobial peptide thanatin fused endolysin PA90 (Tha-PA90) for the control of Acinetobacter baumannii infection in mouse model

Abstract Background This study addresses the urgent need for infection control agents driven by the rise of drug-resistant pathogens such as Acinetobacter baumannii. Our primary aim was to develop and assess a novel endolysin, Tha-PA90, designed to combat these challenges. Methods Tha-PA90 incorpora...

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Bibliographic Details
Main Authors: Jeonghyun Lim, Heejoon Myung, Daejin Lim, Miryoung Song
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Biomedical Science
Subjects:
Endolysin
Thanatin
Tha-PA90
Designed endolysin
A. baumannii infection
Drug-resistant gram-negative pathogen
Online Access:https://doi.org/10.1186/s12929-024-01027-4

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