Aging and Immunity in COVID-19

The COVID-18 pandemic severely affected people older than 65 years, especially those with age-related comorbidities, causing a disproportionate death burden in this age group. The reasons for this difference from other respiratory virus pandemics have been attributed to the aging-induced changes in...

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Bibliographic Details
Main Author: Roberto Paganelli
Format: Article
Language:fas
Published: Qazvin University of Medical Sciences & Health Services 2022-11-01
Series:The Journal of Qazvin University of Medical Sciences
Subjects:
Online Access:https://journal.qums.ac.ir/article-1-3309-en.html
Description
Summary:The COVID-18 pandemic severely affected people older than 65 years, especially those with age-related comorbidities, causing a disproportionate death burden in this age group. The reasons for this difference from other respiratory virus pandemics have been attributed to the aging-induced changes in the immune system, and their effects on the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia. In this brief review, I summarize some of the recent findings throwing light on the relationship between aging, immunity, and the severity of COVID-19.
ISSN:1561-3666