Urinary metabolic characterization of advanced tuberculous meningitis cases in a South African paediatric population

Urinary metabolic characterization of advanced tuberculous meningitis cases in a South African paediatric population

Tuberculous meningitis (TBM) is a severe form of tuberculosis with high neuro-morbidity and mortality, especially among the paediatric population (aged ≤12 years). Little is known of the associated metabolic changes. This study aimed to identify characteristic metabolic markers that differentiate se...

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Bibliographic Details
Main Authors: Simon Isaiah, Du Toit Loots, Mari van Reenen, Regan Solomons, Sabine van Elsland, A. Marceline Tutu van Furth, Martijn van der Kuip, Shayne Mason
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
urine
metabolic
paediatric
tuberculous meningitis (TBM)
untargeted metabolomics
Proton nuclear magnetic resonance (1H NMR) spectroscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1253983/full

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