FBXW7 in breast cancer: mechanism of action and therapeutic potential

Abstract Breast cancer is one of the frequent tumors that seriously endanger the physical and mental well-being in women. F-box and WD repeat domain-containing 7 (FBXW7) is a neoplastic repressor. Serving as a substrate recognition element for ubiquitin ligase, FBXW7 participates in the ubiquitin–pr...

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Bibliographic Details
Main Authors: Siyu Chen, Ping Leng, Jinlin Guo, Hao Zhou
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-023-02767-1

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