Discovery of dibenzyl amide derivatives as novel CXCR4 modulators against inflammatory bowel disease
The CXCR4/CXCL12 chemokine axis demonstrates significant potential in the treatment of inflammatory bowel disease (IBD) due to its crucial roles in inflammatory and immune responses. Modulating the CXCR4/CXCL12 pathway can be an effective therapeutic approach to ameliorate the inflammatory state of...
Main Authors: | Xiaoying Jiang, Liuxin Lu, Jiahui Wang, Meng Yu, Rui Wu, Rui Zhao, Hao Wen, Renren Bai |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-04-01
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Series: | European Journal of Medicinal Chemistry Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772417424000062 |
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