NF-κB c-Rel is a critical regulator of TLR7-induced inflammation in psoriasisResearch in context

NF-κB c-Rel is a critical regulator of TLR7-induced inflammation in psoriasisResearch in context

Summary: Background: Nuclear factor kappa B (NF-κB) c-Rel is a psoriasis susceptibility locus, however mechanisms underlying c-Rel transactivation during disease are poorly understood. Inflammation in psoriasis can be triggered following Toll-like Receptor 7 (TLR7) signalling in dendritic cells (DC...

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Podrobná bibliografie
Hlavní autoři: Angela Rose Liu, Nandini Sarkar, Jordan D. Cress, Tristan J. de Jesus, Ananya Vadlakonda, Joshua T. Centore, Alexis D. Griffith, Bethany Rohr, Thomas S. McCormick, Kevin D. Cooper, Parameswaran Ramakrishnan
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2024-12-01
Edice:EBioMedicine
Témata:
TLR7
NF-κB c-Rel
Inflammation
Psoriasis
Transcription
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2352396424004882

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