NF-κB c-Rel is a critical regulator of TLR7-induced inflammation in psoriasisResearch in context

Summary: Background: Nuclear factor kappa B (NF-κB) c-Rel is a psoriasis susceptibility locus, however mechanisms underlying c-Rel transactivation during disease are poorly understood. Inflammation in psoriasis can be triggered following Toll-like Receptor 7 (TLR7) signalling in dendritic cells (DC...

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Príomhchruthaitheoirí: Angela Rose Liu, Nandini Sarkar, Jordan D. Cress, Tristan J. de Jesus, Ananya Vadlakonda, Joshua T. Centore, Alexis D. Griffith, Bethany Rohr, Thomas S. McCormick, Kevin D. Cooper, Parameswaran Ramakrishnan
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Elsevier 2024-12-01
Sraith:EBioMedicine
Ábhair:
Rochtain ar líne:http://www.sciencedirect.com/science/article/pii/S2352396424004882

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