NF-κB c-Rel is a critical regulator of TLR7-induced inflammation in psoriasisResearch in context

NF-κB c-Rel is a critical regulator of TLR7-induced inflammation in psoriasisResearch in context

Summary: Background: Nuclear factor kappa B (NF-κB) c-Rel is a psoriasis susceptibility locus, however mechanisms underlying c-Rel transactivation during disease are poorly understood. Inflammation in psoriasis can be triggered following Toll-like Receptor 7 (TLR7) signalling in dendritic cells (DC...

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Detalles Bibliográficos
Main Authors: Angela Rose Liu, Nandini Sarkar, Jordan D. Cress, Tristan J. de Jesus, Ananya Vadlakonda, Joshua T. Centore, Alexis D. Griffith, Bethany Rohr, Thomas S. McCormick, Kevin D. Cooper, Parameswaran Ramakrishnan
Formato: Artigo
Idioma:English
Publicado: Elsevier 2024-12-01
Series:EBioMedicine
Subjects:
TLR7
NF-κB c-Rel
Inflammation
Psoriasis
Transcription
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2352396424004882

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