Hantavirus Pulmonary Syndrome, Central Plateau, Southeastern, and Southern Brazil
Hantavirus pulmonary syndrome (HPS) is an increasing health problem in Brazil because of encroachment of sprawling urban, agricultural, and cattle-raising areas into habitats of subfamily Sigmodontinae rodents, which serve as hantavirus reservoirs. From 1993 through June 2007, a total of 884 cases o...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2009-04-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/15/4/08-0289_article |
| _version_ | 1828199173630984192 |
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| author | Luiz T.M. Figueiredo Marcos L. Moreli Ricardo L.M. de Sousa Alessandra A. Borges Glauciane G. de Figueiredo Alex M. Machado Ivani Bisordi Teresa K. Nagasse-Sugahara Akemi Suzuki Luiz E. Pereira Renato P. de Souza Luiza T.M. de Souza Carla T. Braconi Charlotte M. Harsi Paolo M. de Andrade Zanotto |
| author_facet | Luiz T.M. Figueiredo Marcos L. Moreli Ricardo L.M. de Sousa Alessandra A. Borges Glauciane G. de Figueiredo Alex M. Machado Ivani Bisordi Teresa K. Nagasse-Sugahara Akemi Suzuki Luiz E. Pereira Renato P. de Souza Luiza T.M. de Souza Carla T. Braconi Charlotte M. Harsi Paolo M. de Andrade Zanotto |
| author_sort | Luiz T.M. Figueiredo |
| collection | DOAJ |
| description | Hantavirus pulmonary syndrome (HPS) is an increasing health problem in Brazil because of encroachment of sprawling urban, agricultural, and cattle-raising areas into habitats of subfamily Sigmodontinae rodents, which serve as hantavirus reservoirs. From 1993 through June 2007, a total of 884 cases of HPS were reported in Brazil (case-fatality rate 39%). To better understand this emerging disease, we collected 89 human serum samples and 68 rodent lung samples containing antibodies to hantavirus from a 2,500-km-wide area in Brazil. RNA was isolated from human samples and rodent tissues and subjected to reverse transcription–PCR. Partial sequences of nucleocapsid protein and glycoprotein genes from 22 human and 16 rodent sources indicated only Araraquara virus and Juquitiba virus lineages. The case-fatality rate of HPS was higher in the area with Araraquara virus. This virus, which may be the most virulent hantavirus in Brazil, was associated with areas that have had greater anthropogenic changes. |
| first_indexed | 2024-04-12T10:50:57Z |
| format | Article |
| id | doaj.art-50d8eae95dc94f0680ea116a924b85fa |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-04-12T10:50:57Z |
| publishDate | 2009-04-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-50d8eae95dc94f0680ea116a924b85fa2022-12-22T03:36:15ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592009-04-0115456156710.3201/eid1504.080289Hantavirus Pulmonary Syndrome, Central Plateau, Southeastern, and Southern BrazilLuiz T.M. FigueiredoMarcos L. MoreliRicardo L.M. de SousaAlessandra A. BorgesGlauciane G. de FigueiredoAlex M. MachadoIvani BisordiTeresa K. Nagasse-SugaharaAkemi SuzukiLuiz E. PereiraRenato P. de SouzaLuiza T.M. de SouzaCarla T. BraconiCharlotte M. HarsiPaolo M. de Andrade ZanottoHantavirus pulmonary syndrome (HPS) is an increasing health problem in Brazil because of encroachment of sprawling urban, agricultural, and cattle-raising areas into habitats of subfamily Sigmodontinae rodents, which serve as hantavirus reservoirs. From 1993 through June 2007, a total of 884 cases of HPS were reported in Brazil (case-fatality rate 39%). To better understand this emerging disease, we collected 89 human serum samples and 68 rodent lung samples containing antibodies to hantavirus from a 2,500-km-wide area in Brazil. RNA was isolated from human samples and rodent tissues and subjected to reverse transcription–PCR. Partial sequences of nucleocapsid protein and glycoprotein genes from 22 human and 16 rodent sources indicated only Araraquara virus and Juquitiba virus lineages. The case-fatality rate of HPS was higher in the area with Araraquara virus. This virus, which may be the most virulent hantavirus in Brazil, was associated with areas that have had greater anthropogenic changes.https://wwwnc.cdc.gov/eid/article/15/4/08-0289_articleHantavirusAraraquara virusJuquitiba virushantavirus pulmonary syndromeBrazilresearch |
| spellingShingle | Luiz T.M. Figueiredo Marcos L. Moreli Ricardo L.M. de Sousa Alessandra A. Borges Glauciane G. de Figueiredo Alex M. Machado Ivani Bisordi Teresa K. Nagasse-Sugahara Akemi Suzuki Luiz E. Pereira Renato P. de Souza Luiza T.M. de Souza Carla T. Braconi Charlotte M. Harsi Paolo M. de Andrade Zanotto Hantavirus Pulmonary Syndrome, Central Plateau, Southeastern, and Southern Brazil Emerging Infectious Diseases Hantavirus Araraquara virus Juquitiba virus hantavirus pulmonary syndrome Brazil research |
| title | Hantavirus Pulmonary Syndrome, Central Plateau, Southeastern, and Southern Brazil |
| title_full | Hantavirus Pulmonary Syndrome, Central Plateau, Southeastern, and Southern Brazil |
| title_fullStr | Hantavirus Pulmonary Syndrome, Central Plateau, Southeastern, and Southern Brazil |
| title_full_unstemmed | Hantavirus Pulmonary Syndrome, Central Plateau, Southeastern, and Southern Brazil |
| title_short | Hantavirus Pulmonary Syndrome, Central Plateau, Southeastern, and Southern Brazil |
| title_sort | hantavirus pulmonary syndrome central plateau southeastern and southern brazil |
| topic | Hantavirus Araraquara virus Juquitiba virus hantavirus pulmonary syndrome Brazil research |
| url | https://wwwnc.cdc.gov/eid/article/15/4/08-0289_article |
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