Culex quinquefasciatus storage proteins.
Insect storage proteins accumulate at high levels during larval development of holometabolous insects. During metamorphosis they are degraded, supplying energy and amino acids for the completion of adult development. The genome of Culex quinquefasciatus contains eleven storage protein-coding genes....
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3812268?pdf=render |
| _version_ | 1818911773949952000 |
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| author | Larissa A Martins Andréa C Fogaça A Tania Bijovsky Rebeca Carballar-Lejarazú Osvaldo Marinotti André F Cardoso |
| author_facet | Larissa A Martins Andréa C Fogaça A Tania Bijovsky Rebeca Carballar-Lejarazú Osvaldo Marinotti André F Cardoso |
| author_sort | Larissa A Martins |
| collection | DOAJ |
| description | Insect storage proteins accumulate at high levels during larval development of holometabolous insects. During metamorphosis they are degraded, supplying energy and amino acids for the completion of adult development. The genome of Culex quinquefasciatus contains eleven storage protein-coding genes. Their transcripts are more abundant in larvae than in pupae and in adults. In fact, only four of these genes are transcribed in adults, two of which in blood-fed adult females but not in adult males. Transcripts corresponding to all Cx. quinquefasciatus storage proteins were detected by RT-PCR, while mass spectrometric analysis of larval and pupal proteins identified all storage proteins with the exception of one encoded by Cq LSP1.8. Our results indicate that the identified Cx. quinquefasciatus storage protein-coding genes are candidates for identifying regulatory sequences for the development of molecular tools for vector control. |
| first_indexed | 2024-12-19T23:04:02Z |
| format | Article |
| id | doaj.art-50dddcd254ea4cac9d8f48d838b9aa10 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-19T23:04:02Z |
| publishDate | 2013-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-50dddcd254ea4cac9d8f48d838b9aa102022-12-21T20:02:25ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-01810e7766410.1371/journal.pone.0077664Culex quinquefasciatus storage proteins.Larissa A MartinsAndréa C FogaçaA Tania BijovskyRebeca Carballar-LejarazúOsvaldo MarinottiAndré F CardosoInsect storage proteins accumulate at high levels during larval development of holometabolous insects. During metamorphosis they are degraded, supplying energy and amino acids for the completion of adult development. The genome of Culex quinquefasciatus contains eleven storage protein-coding genes. Their transcripts are more abundant in larvae than in pupae and in adults. In fact, only four of these genes are transcribed in adults, two of which in blood-fed adult females but not in adult males. Transcripts corresponding to all Cx. quinquefasciatus storage proteins were detected by RT-PCR, while mass spectrometric analysis of larval and pupal proteins identified all storage proteins with the exception of one encoded by Cq LSP1.8. Our results indicate that the identified Cx. quinquefasciatus storage protein-coding genes are candidates for identifying regulatory sequences for the development of molecular tools for vector control.http://europepmc.org/articles/PMC3812268?pdf=render |
| spellingShingle | Larissa A Martins Andréa C Fogaça A Tania Bijovsky Rebeca Carballar-Lejarazú Osvaldo Marinotti André F Cardoso Culex quinquefasciatus storage proteins. PLoS ONE |
| title | Culex quinquefasciatus storage proteins. |
| title_full | Culex quinquefasciatus storage proteins. |
| title_fullStr | Culex quinquefasciatus storage proteins. |
| title_full_unstemmed | Culex quinquefasciatus storage proteins. |
| title_short | Culex quinquefasciatus storage proteins. |
| title_sort | culex quinquefasciatus storage proteins |
| url | http://europepmc.org/articles/PMC3812268?pdf=render |
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