Electrochemotherapy – supplementary treatment for loco-regional metastasized breast carcinoma administered to concomitant systemic therapy

Electrochemotherapy (ECT) is an established procedure for treating breast cancer loco-regional recurrences following surgical intervention and/or radiotherapy. Limited information is available on ECT application as a concomitant procedure to systemic therapy in recurrent breast cancer. The primary o...

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Bibliographic Details
Main Authors: Grischke Eva-Maria, Röhm Carmen, Stauß Eva, Taran Florin-Andrei, Brucker Sara Y., Wallwiener Diethelm
Format: Article
Language:English
Published: Sciendo 2017-07-01
Series:Radiology and Oncology
Subjects:
Online Access:https://doi.org/10.1515/raon-2017-0027
Description
Summary:Electrochemotherapy (ECT) is an established procedure for treating breast cancer loco-regional recurrences following surgical intervention and/or radiotherapy. Limited information is available on ECT application as a concomitant procedure to systemic therapy in recurrent breast cancer. The primary objective of this study was to determine if the application of ECT in close temporal relation to systemic chemotherapy could lead to increased local and/or systemic side effects. For this purpose we evaluated the safety of ECT as a supplemental local therapy to systemic therapy. ECT local and systemic toxicity and side effects were recorded and whether the anticipated local therapeutic effect of ECT would be influenced by the concomitant use of systemic therapies was investigated.
ISSN:1581-3207