Oral vaccination with heat inactivated Mycobacterium bovis activates the complement system to protect against tuberculosis.

Oral vaccination with heat inactivated Mycobacterium bovis activates the complement system to protect against tuberculosis.

Tuberculosis (TB) remains a pandemic affecting billions of people worldwide, thus stressing the need for new vaccines. Defining the correlates of vaccine protection is essential to achieve this goal. In this study, we used the wild boar model for mycobacterial infection and TB to characterize the pr...

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Main Authors: Beatriz Beltrán-Beck, José de la Fuente, Joseba M Garrido, Alicia Aranaz, Iker Sevilla, Margarita Villar, Mariana Boadella, Ruth C Galindo, José M Pérez de la Lastra, Juan A Moreno-Cid, Isabel G Fernández de Mera, Pilar Alberdi, Gracia Santos, Cristina Ballesteros, Konstantin P Lyashchenko, Esmeralda Minguijón, Beatriz Romero, Lucía de Juan, Lucas Domínguez, Ramón Juste, Christian Gortazar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4026474?pdf=render

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