Identifying clinical subtypes in sepsis-survivors with different one-year outcomes: a secondary latent class analysis of the FROG-ICU cohort

Identifying clinical subtypes in sepsis-survivors with different one-year outcomes: a secondary latent class analysis of the FROG-ICU cohort

Abstract Background Late mortality risk in sepsis-survivors persists for years with high readmission rates and low quality of life. The present study seeks to link the clinical sepsis-survivors heterogeneity with distinct biological profiles at ICU discharge and late adverse events using an unsuperv...

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Bibliographic Details
Main Authors: Sabri Soussi, Divya Sharma, Peter Jüni, Gerald Lebovic, Laurent Brochard, John C. Marshall, Patrick R. Lawler, Margaret Herridge, Niall Ferguson, Lorenzo Del Sorbo, Elodie Feliot, Alexandre Mebazaa, Erica Acton, Jason N. Kennedy, Wei Xu, Etienne Gayat, Claudia C. Dos Santos, the FROG-ICU, CCCTBG trans-trial group study for InFACT - the International Forum for Acute Care Trialists
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Critical Care
Subjects:
Sepsis
Post-intensive care syndrome (PICS)
Biomarkers
Latent profile analysis
Mixture modeling
Prognostic enrichment
Online Access:https://doi.org/10.1186/s13054-022-03972-8

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