Levosimendan inhibits peroxidation in hepatocytes by modulating apoptosis/autophagy interplay.

Levosimendan inhibits peroxidation in hepatocytes by modulating apoptosis/autophagy interplay.

BACKGROUND:Levosimendan protects rat liver against peroxidative injuries through mechanisms related to nitric oxide (NO) production and mitochondrial ATP-dependent K (mitoKATP) channels opening. However, whether levosimendan could modulate the cross-talk between apoptosis and autophagy in the liver...

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Main Authors: Elena Grossini, Kevin Bellofatto, Serena Farruggio, Lorenzo Sigaudo, Patrizia Marotta, Giulia Raina, Veronica De Giuli, David Mary, Piero Pollesello, Rosalba Minisini, Mario Pirisi, Giovanni Vacca
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4400069?pdf=render

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http://europepmc.org/articles/PMC4400069?pdf=render

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