DNA Methylation Analysis to predict Regression of high-grade anal Intraepithelial Neoplasia in HIV+ men (MARINE): a cohort study protocol

DNA Methylation Analysis to predict Regression of high-grade anal Intraepithelial Neoplasia in HIV+ men (MARINE): a cohort study protocol

Introduction Anal cancer precursors, or high-grade anal intraepithelial neoplasia (HGAIN), are highly prevalent in HIV-seropositive (HIV+) men who have sex with men (MSM). Around 30% of lesions regress within 1 year, but current histopathological assessment is unable to distinguish between HGAIN lik...

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Bibliographic Details
Main Authors:	Henry J C de Vries, Johannes Berkhof, Jan M Prins, Maarten F Schim van der Loeff, Renske D M Steenbergen, Carel J M van Noesel, Fernando Dias Gonçalves Lima, Ramon P van der Zee, Stèfanie Dick
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2022-08-01
Series:	BMJ Open
Online Access:	https://bmjopen.bmj.com/content/12/8/e060301.full

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