Anti-platelet agregation: what did we learn from the evidence?

Hyperglycemia and insulin resistance, characteristics of patients with type 2 diabetes mellitus (T2D), produce platelet and endothelial alterations, increasing the risk of thrombotic events. The efficacy and benefit of antiplatelet therapy are well established in patients with atherosclerotic cardio...

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Main Author: Augusto Lavalle Cobo
Format: Article
Language:Spanish
Published: Sello Editorial Lugones 2022-09-01
Series:Revista de la Sociedad Argentina de Diabetes
Subjects:
Online Access:https://revistasad.com/index.php/diabetes/article/view/595
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author Augusto Lavalle Cobo
author_facet Augusto Lavalle Cobo
author_sort Augusto Lavalle Cobo
collection DOAJ
description Hyperglycemia and insulin resistance, characteristics of patients with type 2 diabetes mellitus (T2D), produce platelet and endothelial alterations, increasing the risk of thrombotic events. The efficacy and benefit of antiplatelet therapy are well established in patients with atherosclerotic cardiovascular disease. There is little discussion about the combination of low doses of acetylsalicylic acid (ASA) and a P2Y12 receptor inhibitor in the acute setting of a cardiovascular event. Current evidence seeks to answer the question of how long to maintain this double regimen, mainly in patients with a high risk of bleeding. Maintaining dual antiplatelet therapy for at least one year is recommended after an acute event.This time could be shortened for patients with high bleeding risk and extended for a longer period in patients with a high thrombotic risk. In this scenario, rivaroxaban 2.5 mg b.i.d, can be considered.
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spelling doaj.art-50efca726e8242b49ee49ecb82278d682022-12-22T04:39:03ZspaSello Editorial LugonesRevista de la Sociedad Argentina de Diabetes0325-52472346-94202022-09-01563Sup565610.47196/diab.v56i3Sup.595509Anti-platelet agregation: what did we learn from the evidence?Augusto Lavalle Cobo0Especialista en Cardiología, Coordinador del Servicio de Cardiología, Sanatorio Finochietto, Ciudad Autónoma de Buenos Aires, ArgentinaHyperglycemia and insulin resistance, characteristics of patients with type 2 diabetes mellitus (T2D), produce platelet and endothelial alterations, increasing the risk of thrombotic events. The efficacy and benefit of antiplatelet therapy are well established in patients with atherosclerotic cardiovascular disease. There is little discussion about the combination of low doses of acetylsalicylic acid (ASA) and a P2Y12 receptor inhibitor in the acute setting of a cardiovascular event. Current evidence seeks to answer the question of how long to maintain this double regimen, mainly in patients with a high risk of bleeding. Maintaining dual antiplatelet therapy for at least one year is recommended after an acute event.This time could be shortened for patients with high bleeding risk and extended for a longer period in patients with a high thrombotic risk. In this scenario, rivaroxaban 2.5 mg b.i.d, can be considered.https://revistasad.com/index.php/diabetes/article/view/595antiagregación plaquetariatratamiento
spellingShingle Augusto Lavalle Cobo
Anti-platelet agregation: what did we learn from the evidence?
Revista de la Sociedad Argentina de Diabetes
antiagregación plaquetaria
tratamiento
title Anti-platelet agregation: what did we learn from the evidence?
title_full Anti-platelet agregation: what did we learn from the evidence?
title_fullStr Anti-platelet agregation: what did we learn from the evidence?
title_full_unstemmed Anti-platelet agregation: what did we learn from the evidence?
title_short Anti-platelet agregation: what did we learn from the evidence?
title_sort anti platelet agregation what did we learn from the evidence
topic antiagregación plaquetaria
tratamiento
url https://revistasad.com/index.php/diabetes/article/view/595
work_keys_str_mv AT augustolavallecobo antiplateletagregationwhatdidwelearnfromtheevidence