A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevation
A patient presenting an ST-segment elevation could represent a life-threatening condition in Emergency Department (ED). This case shows how sometimes, a chronic, and more often, an acute abuse of alcohol is related to important harmful effects on myocardial contractility. The authors present a case...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2020-04-01
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| Series: | Emergency Care Journal |
| Subjects: | |
| Online Access: | https://pagepressjournals.org/index.php/ecj/article/view/8596 |
| _version_ | 1818200078489223168 |
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| author | Franco Lai Lorenzo Pelagatti Chiara Pagnini Alessio Baldini Daniele Versari Simone Magazzini |
| author_facet | Franco Lai Lorenzo Pelagatti Chiara Pagnini Alessio Baldini Daniele Versari Simone Magazzini |
| author_sort | Franco Lai |
| collection | DOAJ |
| description | A patient presenting an ST-segment elevation could represent a life-threatening condition in Emergency Department (ED). This case shows how sometimes, a chronic, and more often, an acute abuse of alcohol is related to important harmful effects on myocardial contractility. The authors present a case of a 19-year-old male of oriental-Asiatic origin admitted unconscious to ED with alcoholic fetor: on electrocardiogram a significant and widespread STsegment elevation was observed. A bedside echocardiography showed no abnormalities in segmental kinetics; therefore electrocardiogram- alterations could be related to a coronary spasm. The literature is poor about this effect induced by acute alcohol ingestion: the pathophysiological mechanism at the base of the abnormal muscle contractility, seems to be related to an impairment in cyclic guanosine monophosphate production, although a second and less probable hypothesis could be an altered intracellular concentration of calcium levels. |
| first_indexed | 2024-12-12T02:31:56Z |
| format | Article |
| id | doaj.art-50efe0f7a7884097a9831934c8221e94 |
| institution | Directory Open Access Journal |
| issn | 1826-9826 2282-2054 |
| language | English |
| last_indexed | 2024-12-12T02:31:56Z |
| publishDate | 2020-04-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Emergency Care Journal |
| spelling | doaj.art-50efe0f7a7884097a9831934c8221e942022-12-22T00:41:22ZengPAGEPress PublicationsEmergency Care Journal1826-98262282-20542020-04-0116110.4081/ecj.2020.8596A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevationFranco Lai0Lorenzo Pelagatti1Chiara Pagnini2Alessio Baldini3Daniele Versari4Simone Magazzini5Emergency Department, Santo Stefano Hospital, PratoEmergency Department, Santo Stefano Hospital, PratoSchool of Medicine, University of Florence, FlorenceEmergency Department, Santo Stefano Hospital, PratoEmergency Department, Santo Stefano Hospital, PratoEmergency Department, Santo Stefano Hospital, PratoA patient presenting an ST-segment elevation could represent a life-threatening condition in Emergency Department (ED). This case shows how sometimes, a chronic, and more often, an acute abuse of alcohol is related to important harmful effects on myocardial contractility. The authors present a case of a 19-year-old male of oriental-Asiatic origin admitted unconscious to ED with alcoholic fetor: on electrocardiogram a significant and widespread STsegment elevation was observed. A bedside echocardiography showed no abnormalities in segmental kinetics; therefore electrocardiogram- alterations could be related to a coronary spasm. The literature is poor about this effect induced by acute alcohol ingestion: the pathophysiological mechanism at the base of the abnormal muscle contractility, seems to be related to an impairment in cyclic guanosine monophosphate production, although a second and less probable hypothesis could be an altered intracellular concentration of calcium levels.https://pagepressjournals.org/index.php/ecj/article/view/8596Acute alcohol intoxicationST-segment elevationcoronary vasospasm |
| spellingShingle | Franco Lai Lorenzo Pelagatti Chiara Pagnini Alessio Baldini Daniele Versari Simone Magazzini A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevation Emergency Care Journal Acute alcohol intoxication ST-segment elevation coronary vasospasm |
| title | A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevation |
| title_full | A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevation |
| title_fullStr | A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevation |
| title_full_unstemmed | A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevation |
| title_short | A rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with ST-segment elevation |
| title_sort | rare case of acute alcohol intoxication mimicking an electrocardiographic pattern for acute coronary syndrome with st segment elevation |
| topic | Acute alcohol intoxication ST-segment elevation coronary vasospasm |
| url | https://pagepressjournals.org/index.php/ecj/article/view/8596 |
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