Identification and characterization of prescription drugs that change levels of 7-dehydrocholesterol and desmosterol

Identification and characterization of prescription drugs that change levels of 7-dehydrocholesterol and desmosterol

Regulating blood cholesterol (Chol) levels by pharmacotherapy has successfully improved cardiovascular health. There is growing interest in the role of Chol precursors in the treatment of diseases. One sterol precursor, desmosterol (Des), is a potential pharmacological target for inflammatory and ne...

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Bibliographic Details
Main Authors:	Phillip A. Wages, Hye-Young H. Kim, Zeljka Korade, Ned A. Porter
Format:	Article
Language:	English
Published:	Elsevier 2018-10-01
Series:	Journal of Lipid Research
Subjects:	cholesterol/biosynthesis drug therapy mass spectrometry sterols 24-dehydrocholesterol reductase 7-dehydrocholesterol reductase
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520341833

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