Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis
Objective: The aim of this study was to analyze quantitative sleep changes and their implication on subjective cognitive decline (SCD). Objective sleep patterns were investigated by an actigraph and recorded at the baseline and 2-year after in order to examine specific sleep alterations in SCD.Backg...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-07-01
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| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fnagi.2019.00142/full |
| _version_ | 1819207717716230144 |
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| author | Giovanna Bubbico Giovanna Bubbico Angelo Di Iorio Mariella Lauriola Mariella Lauriola Gianna Sepede Simone Salice Eleonora Spina Eleonora Spina Giacomo Brondi Giacomo Brondi Roberto Esposito Mauro Gianni Perrucci Mauro Gianni Perrucci Armando Tartaro Armando Tartaro Armando Tartaro |
| author_facet | Giovanna Bubbico Giovanna Bubbico Angelo Di Iorio Mariella Lauriola Mariella Lauriola Gianna Sepede Simone Salice Eleonora Spina Eleonora Spina Giacomo Brondi Giacomo Brondi Roberto Esposito Mauro Gianni Perrucci Mauro Gianni Perrucci Armando Tartaro Armando Tartaro Armando Tartaro |
| author_sort | Giovanna Bubbico |
| collection | DOAJ |
| description | Objective: The aim of this study was to analyze quantitative sleep changes and their implication on subjective cognitive decline (SCD). Objective sleep patterns were investigated by an actigraph and recorded at the baseline and 2-year after in order to examine specific sleep alterations in SCD.Background: Sleep disorders are very common among average elderly adults and an altered sleep pattern is known to be a risk factor for future development of mild cognitive impairment (MCI) and dementia. Recent studies have shown how sleep is objectively altered in average senior adults with SCD, without any other significant change in cognition and behavior or brain structure. Considering that both SCD and disrupted sleep are risk factors for future MCI and dementia, with sleep only as a modifiable risk factor, further research is required to deeply investigate the interaction between sleep and SCD.Methods: Among 70 community-dwelling elderly individuals who had been enrolled at baseline, 35 (64.6 ± 5.6 years, 15 M/20 F) underwent a complete neuropsychological battery and 1-week wrist actigraphy recording 2 years later during the follow-up stage. Individuals were divided into two groups according to their SCD Questionnaire (SCD-Q) score. Sleep hours, sleep efficiency and onset latency, napping and time awake after sleep onset (WASO) were collected. All individuals underwent structural magnetic resonance imaging (MRI) examination to exclude brain disorders. Data collection was performed at baseline and after 2 years at the follow-up phase.Results: A significantly different night sleep time between the two groups was observed: SCD showed a lower total sleep time (TST) than non-SCD subjects. Moreover, a total time spent in bed (TIB) was significantly lower in SCD subjects over 2 years of observation.Conclusions: Objective changes over time of the sleep pattern, specifically TIB and TST, are present in SCD individuals. The results of the study show that sleep alterations are common in SCD and underline the clinical importance of screening in order to assess sleep alterations as well as improve sleep in average adults with SCD complaints. |
| first_indexed | 2024-12-23T05:27:56Z |
| format | Article |
| id | doaj.art-50fcb4182d064be994c0b9de9bbc8c95 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-12-23T05:27:56Z |
| publishDate | 2019-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-50fcb4182d064be994c0b9de9bbc8c952022-12-21T17:58:32ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652019-07-011110.3389/fnagi.2019.00142417188Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal AnalysisGiovanna Bubbico0Giovanna Bubbico1Angelo Di Iorio2Mariella Lauriola3Mariella Lauriola4Gianna Sepede5Simone Salice6Eleonora Spina7Eleonora Spina8Giacomo Brondi9Giacomo Brondi10Roberto Esposito11Mauro Gianni Perrucci12Mauro Gianni Perrucci13Armando Tartaro14Armando Tartaro15Armando Tartaro16Department of Neuroscience, Imaging and Clinical Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyInstitute for Advanced Biomedical Technologies (ITAB), “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyDepartment of Medicine and Science of Aging, “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyDepartment of Neuroscience, Imaging and Clinical Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyMomentum for Mental Health, La Selva, Palo Alto, CA, United StatesDepartment of Neuroscience, Imaging and Clinical Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyDepartment of Neuroscience, Imaging and Clinical Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyDepartment of Neuroscience, Imaging and Clinical Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyDepartment of Medicine and Science of Aging, “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyDepartment of Neuroscience, Imaging and Clinical Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyDepartment of Medicine and Science of Aging, “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyDepartment of Radiology, Azienda Ospedaliera Ospedali Riuniti Marche Nord, Pesaro, ItalyDepartment of Neuroscience, Imaging and Clinical Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyInstitute for Advanced Biomedical Technologies (ITAB), “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyDepartment of Neuroscience, Imaging and Clinical Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyInstitute for Advanced Biomedical Technologies (ITAB), “G. d’Annunzio” University of Chieti-Pescara, Chieti, ItalyRadiology Units, Popoli Hospital, Popoli, ItalyObjective: The aim of this study was to analyze quantitative sleep changes and their implication on subjective cognitive decline (SCD). Objective sleep patterns were investigated by an actigraph and recorded at the baseline and 2-year after in order to examine specific sleep alterations in SCD.Background: Sleep disorders are very common among average elderly adults and an altered sleep pattern is known to be a risk factor for future development of mild cognitive impairment (MCI) and dementia. Recent studies have shown how sleep is objectively altered in average senior adults with SCD, without any other significant change in cognition and behavior or brain structure. Considering that both SCD and disrupted sleep are risk factors for future MCI and dementia, with sleep only as a modifiable risk factor, further research is required to deeply investigate the interaction between sleep and SCD.Methods: Among 70 community-dwelling elderly individuals who had been enrolled at baseline, 35 (64.6 ± 5.6 years, 15 M/20 F) underwent a complete neuropsychological battery and 1-week wrist actigraphy recording 2 years later during the follow-up stage. Individuals were divided into two groups according to their SCD Questionnaire (SCD-Q) score. Sleep hours, sleep efficiency and onset latency, napping and time awake after sleep onset (WASO) were collected. All individuals underwent structural magnetic resonance imaging (MRI) examination to exclude brain disorders. Data collection was performed at baseline and after 2 years at the follow-up phase.Results: A significantly different night sleep time between the two groups was observed: SCD showed a lower total sleep time (TST) than non-SCD subjects. Moreover, a total time spent in bed (TIB) was significantly lower in SCD subjects over 2 years of observation.Conclusions: Objective changes over time of the sleep pattern, specifically TIB and TST, are present in SCD individuals. The results of the study show that sleep alterations are common in SCD and underline the clinical importance of screening in order to assess sleep alterations as well as improve sleep in average adults with SCD complaints.https://www.frontiersin.org/article/10.3389/fnagi.2019.00142/fullsleepagingpreventiondementiasubjective cognitive decline |
| spellingShingle | Giovanna Bubbico Giovanna Bubbico Angelo Di Iorio Mariella Lauriola Mariella Lauriola Gianna Sepede Simone Salice Eleonora Spina Eleonora Spina Giacomo Brondi Giacomo Brondi Roberto Esposito Mauro Gianni Perrucci Mauro Gianni Perrucci Armando Tartaro Armando Tartaro Armando Tartaro Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis Frontiers in Aging Neuroscience sleep aging prevention dementia subjective cognitive decline |
| title | Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis |
| title_full | Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis |
| title_fullStr | Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis |
| title_full_unstemmed | Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis |
| title_short | Subjective Cognitive Decline and Nighttime Sleep Alterations, a Longitudinal Analysis |
| title_sort | subjective cognitive decline and nighttime sleep alterations a longitudinal analysis |
| topic | sleep aging prevention dementia subjective cognitive decline |
| url | https://www.frontiersin.org/article/10.3389/fnagi.2019.00142/full |
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