Gut microbiota: a non-target victim of pesticide-induced toxicity
ABSTRACTThe human gut microbiota can be potentially disrupted due to exposure of various environmental contaminants, including pesticides. These contaminants enter into non-target species in multiple ways and cause potential health risks. The gut microbiota-derived metabolites have a significant rol...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Gut Microbes |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/19490976.2023.2187578 |
| _version_ | 1797236645740675072 |
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| author | Tusha Sharma Nagabhishek Sirpu Natesh Ramesh Pothuraju Surinder K. Batra Satyanarayana Rachagani |
| author_facet | Tusha Sharma Nagabhishek Sirpu Natesh Ramesh Pothuraju Surinder K. Batra Satyanarayana Rachagani |
| author_sort | Tusha Sharma |
| collection | DOAJ |
| description | ABSTRACTThe human gut microbiota can be potentially disrupted due to exposure of various environmental contaminants, including pesticides. These contaminants enter into non-target species in multiple ways and cause potential health risks. The gut microbiota-derived metabolites have a significant role in maintaining the host’s health by regulating metabolic homeostasis. An imbalance in this homeostasis can result in the development of various diseases and their pathogenesis. Pesticides have hazardous effects on the host’s gut microbiota, which is evident in a few recent studies. Therefore, there is an urgent need to explore the effect of pesticide on gut microbiota-mediated metabolic changes in the host, which may provide a better understanding of pesticide-induced toxicity. The present review summarizes the pesticide-induced effects on gut microbiota, which in turn, induces changes in the release of their secondary metabolites that could lead to various host health effects. |
| first_indexed | 2024-03-11T14:20:17Z |
| format | Article |
| id | doaj.art-51031272381144bfb605f820c0d04f78 |
| institution | Directory Open Access Journal |
| issn | 1949-0976 1949-0984 |
| language | English |
| last_indexed | 2024-04-24T17:07:09Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Gut Microbes |
| spelling | doaj.art-51031272381144bfb605f820c0d04f782024-03-28T22:38:20ZengTaylor & Francis GroupGut Microbes1949-09761949-09842023-12-0115110.1080/19490976.2023.2187578Gut microbiota: a non-target victim of pesticide-induced toxicityTusha Sharma0Nagabhishek Sirpu Natesh1Ramesh Pothuraju2Surinder K. Batra3Satyanarayana Rachagani4Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USADepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USADepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USADepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USADepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USAABSTRACTThe human gut microbiota can be potentially disrupted due to exposure of various environmental contaminants, including pesticides. These contaminants enter into non-target species in multiple ways and cause potential health risks. The gut microbiota-derived metabolites have a significant role in maintaining the host’s health by regulating metabolic homeostasis. An imbalance in this homeostasis can result in the development of various diseases and their pathogenesis. Pesticides have hazardous effects on the host’s gut microbiota, which is evident in a few recent studies. Therefore, there is an urgent need to explore the effect of pesticide on gut microbiota-mediated metabolic changes in the host, which may provide a better understanding of pesticide-induced toxicity. The present review summarizes the pesticide-induced effects on gut microbiota, which in turn, induces changes in the release of their secondary metabolites that could lead to various host health effects.https://www.tandfonline.com/doi/10.1080/19490976.2023.2187578Gut microbiotapersistent organic pollutantspesticidesorganochlorine pesticidesorganophosphate pesticidesheavy metals |
| spellingShingle | Tusha Sharma Nagabhishek Sirpu Natesh Ramesh Pothuraju Surinder K. Batra Satyanarayana Rachagani Gut microbiota: a non-target victim of pesticide-induced toxicity Gut Microbes Gut microbiota persistent organic pollutants pesticides organochlorine pesticides organophosphate pesticides heavy metals |
| title | Gut microbiota: a non-target victim of pesticide-induced toxicity |
| title_full | Gut microbiota: a non-target victim of pesticide-induced toxicity |
| title_fullStr | Gut microbiota: a non-target victim of pesticide-induced toxicity |
| title_full_unstemmed | Gut microbiota: a non-target victim of pesticide-induced toxicity |
| title_short | Gut microbiota: a non-target victim of pesticide-induced toxicity |
| title_sort | gut microbiota a non target victim of pesticide induced toxicity |
| topic | Gut microbiota persistent organic pollutants pesticides organochlorine pesticides organophosphate pesticides heavy metals |
| url | https://www.tandfonline.com/doi/10.1080/19490976.2023.2187578 |
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