Is seasonal vaccination a contributing factor to the selection of influenza epidemic variants?
Influenza A/H3N2 viruses are the most common and virulent subtypes for humans. Antigenic drift, changes in antigenicity through the accumulation of mutations in the hemagglutinin (HA) gene is chiefly responsible for the continuing circulation of A/H3N2 viruses, resulting in frequent updates of vacci...
Main Authors: | Yong Chong, Hideyuki Ikematsu |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2018-03-01
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Series: | Human Vaccines & Immunotherapeutics |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/21645515.2017.1373228 |
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