Microbial Regulation of Enteric Eosinophils and Its Impact on Tissue Remodeling and Th2 Immunity

Microbial Regulation of Enteric Eosinophils and Its Impact on Tissue Remodeling and Th2 Immunity

Eosinophils have emerged as multifaceted cells that contribute to tissue homeostasis. However, the impact of the microbiota on their frequency and function at mucosal sites remains unclear. Here, we investigated the role of the microbiota in the regulation of enteric eosinophils. We found that small...

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Bibliographic Details
Main Authors: Rodrigo Jiménez-Saiz, Varun C. Anipindi, Heather Galipeau, Yosef Ellenbogen, Roopali Chaudhary, Joshua F. Koenig, Melissa E. Gordon, Tina D. Walker, Talveer S. Mandur, Soumeya Abed, Alison Humbles, Derek K. Chu, Jonas Erjefält, Kjetil Ask, Elena F. Verdú, Manel Jordana
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
eosinophils
microbiota
tissue remodeling
small intestine
allergy
germfree
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00155/full

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