PitNETs and the gut microbiota: potential connections, future directions
The role of the gut microbiome has been widely discussed in numerous works of literature. The biggest concern is the association of the gut microbiome with the central nervous system through the microbiome-brain-gut axis in the past ten years. As more and more research has been done on the relations...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-11-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1255911/full |
| _version_ | 1797635570428542976 |
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| author | Ding Nie Chuzhong Li Yazhuo Zhang |
| author_facet | Ding Nie Chuzhong Li Yazhuo Zhang |
| author_sort | Ding Nie |
| collection | DOAJ |
| description | The role of the gut microbiome has been widely discussed in numerous works of literature. The biggest concern is the association of the gut microbiome with the central nervous system through the microbiome-brain-gut axis in the past ten years. As more and more research has been done on the relationship between the disease of the central nervous system and gut microbes. This fact is being revealed that gut microbes seem to play an important role from the onset and progression of the disease to clinical symptoms, and new treatments. As a special tumor of the central nervous system, pituitary neuroendocrine tumors (PitNETs)are closely related to metabolism, endocrinology, and immunity. These factors are the vectors through which intestinal microbes interact with the central nervous system. However, little is known about the effects of gut microbes on the PitNET. In this review, the relationship of gut microbiota in PitNETs is introduced, the potential effects of the gut-brain axis in this relationship are analyzed, and future research directions are presented. |
| first_indexed | 2024-03-11T12:23:41Z |
| format | Article |
| id | doaj.art-51040355e49f407b960ee8a4fd7bfa99 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-03-11T12:23:41Z |
| publishDate | 2023-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-51040355e49f407b960ee8a4fd7bfa992023-11-06T16:05:24ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-11-011410.3389/fendo.2023.12559111255911PitNETs and the gut microbiota: potential connections, future directionsDing NieChuzhong LiYazhuo ZhangThe role of the gut microbiome has been widely discussed in numerous works of literature. The biggest concern is the association of the gut microbiome with the central nervous system through the microbiome-brain-gut axis in the past ten years. As more and more research has been done on the relationship between the disease of the central nervous system and gut microbes. This fact is being revealed that gut microbes seem to play an important role from the onset and progression of the disease to clinical symptoms, and new treatments. As a special tumor of the central nervous system, pituitary neuroendocrine tumors (PitNETs)are closely related to metabolism, endocrinology, and immunity. These factors are the vectors through which intestinal microbes interact with the central nervous system. However, little is known about the effects of gut microbes on the PitNET. In this review, the relationship of gut microbiota in PitNETs is introduced, the potential effects of the gut-brain axis in this relationship are analyzed, and future research directions are presented.https://www.frontiersin.org/articles/10.3389/fendo.2023.1255911/fullintestinal floragut microbiotapituitary neuroendocrine tumor (PitNET)gut-brain axispituitary tumor |
| spellingShingle | Ding Nie Chuzhong Li Yazhuo Zhang PitNETs and the gut microbiota: potential connections, future directions Frontiers in Endocrinology intestinal flora gut microbiota pituitary neuroendocrine tumor (PitNET) gut-brain axis pituitary tumor |
| title | PitNETs and the gut microbiota: potential connections, future directions |
| title_full | PitNETs and the gut microbiota: potential connections, future directions |
| title_fullStr | PitNETs and the gut microbiota: potential connections, future directions |
| title_full_unstemmed | PitNETs and the gut microbiota: potential connections, future directions |
| title_short | PitNETs and the gut microbiota: potential connections, future directions |
| title_sort | pitnets and the gut microbiota potential connections future directions |
| topic | intestinal flora gut microbiota pituitary neuroendocrine tumor (PitNET) gut-brain axis pituitary tumor |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1255911/full |
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