TRIB1 regulates liver regeneration by antagonizing the NRF2-mediated antioxidant response
Abstract Robust regenerative response post liver injuries facilitates the architectural and functional recovery of the liver. Intrahepatic redox homeostasis plays a key role in liver regeneration. In the present study, we investigated the contributory role of Tribbles homolog 1 (Trib1), a pseudokina...
Main Authors: | Xinyue Sun, Shuai Wang, Xiulian Miao, Sheng Zeng, Yan Guo, Anqi Zhou, Ying Chen, Yifei Chen, Fangqiao Lv, Zhiwen Fan, Yutong Wang, Yong Xu, Zilong Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-06-01
|
Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-05896-9 |
Similar Items
-
Trib-U-lations.
by: Chan, Matthias Yong Shun.
Published: (2010) -
Phosphatidic acid-enabled MKL1 contributes to liver regeneration: Translational implication in liver failure
by: Jiawen Zhou, et al.
Published: (2024-01-01) -
Dual Regulation of Tank Binding Kinase 1 by BRG1 in Hepatocytes Contributes to Reactive Oxygen Species Production
by: Fangqiao Lv, et al.
Published: (2021-10-01) -
Osthole Antagonizes Microglial Activation in an NRF2-Dependent Manner
by: Chuan-Hsiu Liu, et al.
Published: (2023-01-01) -
Choline Kinase Alpha Is a Novel Transcriptional Target of the Brg1 in Hepatocyte: Implication in Liver Regeneration
by: Ming Kong, et al.
Published: (2021-08-01)