Dietary reference values for thiamin
Abstract Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derived dietary reference values (DRVs) for thiamin (vitamin B1). The Panel considers that data from depletion–repletion studies in adults on the amount of dietary thiamin in...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-12-01
|
| Series: | EFSA Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.2903/j.efsa.2016.4653 |
| _version_ | 1818573098796974080 |
|---|---|
| author | EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) Dominique Turck Jean‐Louis Bresson Barbara Burlingame Tara Dean Susan Fairweather‐Tait Marina Heinonen Karen Ildico Hirsch‐Ernst Inge Mangelsdorf Harry J McArdle Androniki Naska Grażyna Nowicka Kristina Pentieva Yolanda Sanz Alfonso Siani Anders Sjödin Martin Stern Daniel Tomé Henk Van Loveren Marco Vinceti Peter Willatts Christel Lamberg‐Allardt Hildegard Przyrembel Inge Tetens Jelena Gudelj Rakic Sofia Ioannidou Agnès deSesmaisons‐Lecarré Annette Cecilia Forss Monika Neuhäuser‐Berthold |
| author_facet | EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) Dominique Turck Jean‐Louis Bresson Barbara Burlingame Tara Dean Susan Fairweather‐Tait Marina Heinonen Karen Ildico Hirsch‐Ernst Inge Mangelsdorf Harry J McArdle Androniki Naska Grażyna Nowicka Kristina Pentieva Yolanda Sanz Alfonso Siani Anders Sjödin Martin Stern Daniel Tomé Henk Van Loveren Marco Vinceti Peter Willatts Christel Lamberg‐Allardt Hildegard Przyrembel Inge Tetens Jelena Gudelj Rakic Sofia Ioannidou Agnès deSesmaisons‐Lecarré Annette Cecilia Forss Monika Neuhäuser‐Berthold |
| author_sort | EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) |
| collection | DOAJ |
| description | Abstract Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derived dietary reference values (DRVs) for thiamin (vitamin B1). The Panel considers that data from depletion–repletion studies in adults on the amount of dietary thiamin intake associated with the erythrocyte transketolase activity coefficient (αETK) < 1.15, generally considered to reflect an adequate thiamin status, or with the restoration of normal (baseline) erythrocyte transketolase activity, without a sharp increase in urinary thiamin excretion, can be used to estimate thiamin requirement. In the absence of new scientific evidence, the Panel endorses the average requirement (AR) of 0.072 mg/MJ (0.3 mg/1,000 kcal) for all adults proposed by the Scientific Committee for Food (SCF) in 1993 on the basis of one depletion–repletion study, in which both αETK and urinary thiamin excretion were measured. Results from other depletion–repletion studies are in agreement with this value. The Panel agrees on the coefficient of variation of 20% used by the SCF to cover uncertainties related to distribution of thiamin requirements in the general population, and endorses the population reference intake (PRI) of 0.1 mg/MJ (0.4 mg/1,000 kcal) set by the SCF for all adults. The same AR and PRI as for adults, expressed in mg/MJ, are proposed for infants aged 7–11 months, children aged 1 to < 18 years, and during pregnancy and lactation, under the assumption that the relationship between thiamin requirement and energy requirement is the same in all population groups. |
| first_indexed | 2024-12-15T00:06:33Z |
| format | Article |
| id | doaj.art-51099d6b81674980b3b134e11f45dea1 |
| institution | Directory Open Access Journal |
| issn | 1831-4732 |
| language | English |
| last_indexed | 2024-12-15T00:06:33Z |
| publishDate | 2016-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | EFSA Journal |
| spelling | doaj.art-51099d6b81674980b3b134e11f45dea12022-12-21T22:42:43ZengWileyEFSA Journal1831-47322016-12-011412n/an/a10.2903/j.efsa.2016.4653Dietary reference values for thiaminEFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)Dominique TurckJean‐Louis BressonBarbara BurlingameTara DeanSusan Fairweather‐TaitMarina HeinonenKaren Ildico Hirsch‐ErnstInge MangelsdorfHarry J McArdleAndroniki NaskaGrażyna NowickaKristina PentievaYolanda SanzAlfonso SianiAnders SjödinMartin SternDaniel ToméHenk Van LoverenMarco VincetiPeter WillattsChristel Lamberg‐AllardtHildegard PrzyrembelInge TetensJelena Gudelj RakicSofia IoannidouAgnès deSesmaisons‐LecarréAnnette Cecilia ForssMonika Neuhäuser‐BertholdAbstract Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derived dietary reference values (DRVs) for thiamin (vitamin B1). The Panel considers that data from depletion–repletion studies in adults on the amount of dietary thiamin intake associated with the erythrocyte transketolase activity coefficient (αETK) < 1.15, generally considered to reflect an adequate thiamin status, or with the restoration of normal (baseline) erythrocyte transketolase activity, without a sharp increase in urinary thiamin excretion, can be used to estimate thiamin requirement. In the absence of new scientific evidence, the Panel endorses the average requirement (AR) of 0.072 mg/MJ (0.3 mg/1,000 kcal) for all adults proposed by the Scientific Committee for Food (SCF) in 1993 on the basis of one depletion–repletion study, in which both αETK and urinary thiamin excretion were measured. Results from other depletion–repletion studies are in agreement with this value. The Panel agrees on the coefficient of variation of 20% used by the SCF to cover uncertainties related to distribution of thiamin requirements in the general population, and endorses the population reference intake (PRI) of 0.1 mg/MJ (0.4 mg/1,000 kcal) set by the SCF for all adults. The same AR and PRI as for adults, expressed in mg/MJ, are proposed for infants aged 7–11 months, children aged 1 to < 18 years, and during pregnancy and lactation, under the assumption that the relationship between thiamin requirement and energy requirement is the same in all population groups.https://doi.org/10.2903/j.efsa.2016.4653thiaminaverage requirementpopulation reference intakedietary reference value |
| spellingShingle | EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) Dominique Turck Jean‐Louis Bresson Barbara Burlingame Tara Dean Susan Fairweather‐Tait Marina Heinonen Karen Ildico Hirsch‐Ernst Inge Mangelsdorf Harry J McArdle Androniki Naska Grażyna Nowicka Kristina Pentieva Yolanda Sanz Alfonso Siani Anders Sjödin Martin Stern Daniel Tomé Henk Van Loveren Marco Vinceti Peter Willatts Christel Lamberg‐Allardt Hildegard Przyrembel Inge Tetens Jelena Gudelj Rakic Sofia Ioannidou Agnès deSesmaisons‐Lecarré Annette Cecilia Forss Monika Neuhäuser‐Berthold Dietary reference values for thiamin EFSA Journal thiamin average requirement population reference intake dietary reference value |
| title | Dietary reference values for thiamin |
| title_full | Dietary reference values for thiamin |
| title_fullStr | Dietary reference values for thiamin |
| title_full_unstemmed | Dietary reference values for thiamin |
| title_short | Dietary reference values for thiamin |
| title_sort | dietary reference values for thiamin |
| topic | thiamin average requirement population reference intake dietary reference value |
| url | https://doi.org/10.2903/j.efsa.2016.4653 |
| work_keys_str_mv | AT efsapanelondieteticproductsnutritionandallergiesnda dietaryreferencevaluesforthiamin AT dominiqueturck dietaryreferencevaluesforthiamin AT jeanlouisbresson dietaryreferencevaluesforthiamin AT barbaraburlingame dietaryreferencevaluesforthiamin AT taradean dietaryreferencevaluesforthiamin AT susanfairweathertait dietaryreferencevaluesforthiamin AT marinaheinonen dietaryreferencevaluesforthiamin AT karenildicohirschernst dietaryreferencevaluesforthiamin AT ingemangelsdorf dietaryreferencevaluesforthiamin AT harryjmcardle dietaryreferencevaluesforthiamin AT andronikinaska dietaryreferencevaluesforthiamin AT grazynanowicka dietaryreferencevaluesforthiamin AT kristinapentieva dietaryreferencevaluesforthiamin AT yolandasanz dietaryreferencevaluesforthiamin AT alfonsosiani dietaryreferencevaluesforthiamin AT anderssjodin dietaryreferencevaluesforthiamin AT martinstern dietaryreferencevaluesforthiamin AT danieltome dietaryreferencevaluesforthiamin AT henkvanloveren dietaryreferencevaluesforthiamin AT marcovinceti dietaryreferencevaluesforthiamin AT peterwillatts dietaryreferencevaluesforthiamin AT christellambergallardt dietaryreferencevaluesforthiamin AT hildegardprzyrembel dietaryreferencevaluesforthiamin AT ingetetens dietaryreferencevaluesforthiamin AT jelenagudeljrakic dietaryreferencevaluesforthiamin AT sofiaioannidou dietaryreferencevaluesforthiamin AT agnesdesesmaisonslecarre dietaryreferencevaluesforthiamin AT annettececiliaforss dietaryreferencevaluesforthiamin AT monikaneuhauserberthold dietaryreferencevaluesforthiamin |