Immunohistochemical expression of types I and III collagen antibodies in the temporomandibular joint disc of human foetuses

The objective was to study the morphology of the articular disc and analyse the immunohistochemical expression of types I and III collagen markers in the temporomandibular joint (TMJ) disc of human foetuses of different gestational ages. Twenty TMJ from human foetuses supplied by Universidade Federa...

Full description

Bibliographic Details
Main Authors: L.O.C. de Moraes, F.R. Lodi, T. S. Gomes, C.T.F. Oshima, S.R. Marques, C.L.P. Lancellotti, J.F. Rodriguez-Vázquez, J.R. Mérida-Velasco, L.G. Alonso
Format: Article
Language:English
Published: PAGEPress Publications 2011-07-01
Series:European Journal of Histochemistry
Subjects:
Online Access:http://www.ejh.it/index.php/ejh/article/view/1824
Description
Summary:The objective was to study the morphology of the articular disc and analyse the immunohistochemical expression of types I and III collagen markers in the temporomandibular joint (TMJ) disc of human foetuses of different gestational ages. Twenty TMJ from human foetuses supplied by Universidade Federal de Uberaba with gestational ages from 17 to 24 weeks were studied. The gestational age of the foetuses was determined by measuring the crown-rump (CR) length. Macroscopically, the foetuses were fixed in 10% formalin solution and dissected by removing the skin and subcutaneous tissue and exposing the deep structures. Immunohistochemical markers of type I and III were used to characterize the existence of collagen fibres. Analysis of the immunohistochemical markers of types I and III collagen revealed the presence of heterotypical fibril networks.
ISSN:1121-760X
2038-8306