Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo

Several cutaneous manifestations in patients undergoing COVID-19 vaccination have been described in the literature. Herein, we presented a case of new-onset vitiligo that occurred after the second dose of the Comirnaty vaccine. An updated literature search revealed the occurrence of a total of 16 ca...

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Main Authors: Laura Macca, Lucia Peterle, Manuela Ceccarelli, Ylenia Ingrasciotta, Giuseppe Nunnari, Claudio Guarneri
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/10/1647
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author Laura Macca
Lucia Peterle
Manuela Ceccarelli
Ylenia Ingrasciotta
Giuseppe Nunnari
Claudio Guarneri
author_facet Laura Macca
Lucia Peterle
Manuela Ceccarelli
Ylenia Ingrasciotta
Giuseppe Nunnari
Claudio Guarneri
author_sort Laura Macca
collection DOAJ
description Several cutaneous manifestations in patients undergoing COVID-19 vaccination have been described in the literature. Herein, we presented a case of new-onset vitiligo that occurred after the second dose of the Comirnaty vaccine. An updated literature search revealed the occurrence of a total of 16 cases, including new-onset or worsening of preexisting vitiligo. Given the autoimmune pathogenesis of the disease, we reviewed and discussed the potential role of the vaccine prophylaxis as a trigger for the development of such hypopigmented skin lesions.
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spelling doaj.art-510bb54825bd4a00be4cda629675be602023-11-24T03:03:35ZengMDPI AGVaccines2076-393X2022-09-011010164710.3390/vaccines10101647Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated VitiligoLaura Macca0Lucia Peterle1Manuela Ceccarelli2Ylenia Ingrasciotta3Giuseppe Nunnari4Claudio Guarneri5Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, ItalyDepartment of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, ItalyDepartment of Clinical and Experimental Medicine, Unit of Infectious Diseases, University of Catania, Catania, Italy C/O ARNAS “Garibaldi”, “Nesima” Hospital, Via Palermo 636, 95122 Catania, ItalyDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Pharmacology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, ItalyDepartment of Clinical and Experimental Medicine, Unit of Infectious Diseases, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, ItalyDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Dermatology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, ItalySeveral cutaneous manifestations in patients undergoing COVID-19 vaccination have been described in the literature. Herein, we presented a case of new-onset vitiligo that occurred after the second dose of the Comirnaty vaccine. An updated literature search revealed the occurrence of a total of 16 cases, including new-onset or worsening of preexisting vitiligo. Given the autoimmune pathogenesis of the disease, we reviewed and discussed the potential role of the vaccine prophylaxis as a trigger for the development of such hypopigmented skin lesions.https://www.mdpi.com/2076-393X/10/10/1647autoimmunityautoimmune diseasesvitiligovaccineCOVID-19
spellingShingle Laura Macca
Lucia Peterle
Manuela Ceccarelli
Ylenia Ingrasciotta
Giuseppe Nunnari
Claudio Guarneri
Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo
Vaccines
autoimmunity
autoimmune diseases
vitiligo
vaccine
COVID-19
title Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo
title_full Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo
title_fullStr Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo
title_full_unstemmed Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo
title_short Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo
title_sort vitiligo like lesions and covid 19 case report and review of vaccination and infection associated vitiligo
topic autoimmunity
autoimmune diseases
vitiligo
vaccine
COVID-19
url https://www.mdpi.com/2076-393X/10/10/1647
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