Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo
Several cutaneous manifestations in patients undergoing COVID-19 vaccination have been described in the literature. Herein, we presented a case of new-onset vitiligo that occurred after the second dose of the Comirnaty vaccine. An updated literature search revealed the occurrence of a total of 16 ca...
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MDPI AG
2022-09-01
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Series: | Vaccines |
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Online Access: | https://www.mdpi.com/2076-393X/10/10/1647 |
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author | Laura Macca Lucia Peterle Manuela Ceccarelli Ylenia Ingrasciotta Giuseppe Nunnari Claudio Guarneri |
author_facet | Laura Macca Lucia Peterle Manuela Ceccarelli Ylenia Ingrasciotta Giuseppe Nunnari Claudio Guarneri |
author_sort | Laura Macca |
collection | DOAJ |
description | Several cutaneous manifestations in patients undergoing COVID-19 vaccination have been described in the literature. Herein, we presented a case of new-onset vitiligo that occurred after the second dose of the Comirnaty vaccine. An updated literature search revealed the occurrence of a total of 16 cases, including new-onset or worsening of preexisting vitiligo. Given the autoimmune pathogenesis of the disease, we reviewed and discussed the potential role of the vaccine prophylaxis as a trigger for the development of such hypopigmented skin lesions. |
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format | Article |
id | doaj.art-510bb54825bd4a00be4cda629675be60 |
institution | Directory Open Access Journal |
issn | 2076-393X |
language | English |
last_indexed | 2024-03-09T19:24:49Z |
publishDate | 2022-09-01 |
publisher | MDPI AG |
record_format | Article |
series | Vaccines |
spelling | doaj.art-510bb54825bd4a00be4cda629675be602023-11-24T03:03:35ZengMDPI AGVaccines2076-393X2022-09-011010164710.3390/vaccines10101647Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated VitiligoLaura Macca0Lucia Peterle1Manuela Ceccarelli2Ylenia Ingrasciotta3Giuseppe Nunnari4Claudio Guarneri5Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, ItalyDepartment of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, ItalyDepartment of Clinical and Experimental Medicine, Unit of Infectious Diseases, University of Catania, Catania, Italy C/O ARNAS “Garibaldi”, “Nesima” Hospital, Via Palermo 636, 95122 Catania, ItalyDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Pharmacology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, ItalyDepartment of Clinical and Experimental Medicine, Unit of Infectious Diseases, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, ItalyDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, Section of Dermatology, University of Messina, Messina, Italy C/O A.O.U.P. “Gaetano Martino”, Via Consolare Valeria, 98125 Messina, ItalySeveral cutaneous manifestations in patients undergoing COVID-19 vaccination have been described in the literature. Herein, we presented a case of new-onset vitiligo that occurred after the second dose of the Comirnaty vaccine. An updated literature search revealed the occurrence of a total of 16 cases, including new-onset or worsening of preexisting vitiligo. Given the autoimmune pathogenesis of the disease, we reviewed and discussed the potential role of the vaccine prophylaxis as a trigger for the development of such hypopigmented skin lesions.https://www.mdpi.com/2076-393X/10/10/1647autoimmunityautoimmune diseasesvitiligovaccineCOVID-19 |
spellingShingle | Laura Macca Lucia Peterle Manuela Ceccarelli Ylenia Ingrasciotta Giuseppe Nunnari Claudio Guarneri Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo Vaccines autoimmunity autoimmune diseases vitiligo vaccine COVID-19 |
title | Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo |
title_full | Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo |
title_fullStr | Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo |
title_full_unstemmed | Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo |
title_short | Vitiligo-like Lesions and COVID-19: Case Report and Review of Vaccination- and Infection-Associated Vitiligo |
title_sort | vitiligo like lesions and covid 19 case report and review of vaccination and infection associated vitiligo |
topic | autoimmunity autoimmune diseases vitiligo vaccine COVID-19 |
url | https://www.mdpi.com/2076-393X/10/10/1647 |
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