The impact of vitamin D on the etiopathogenesis and the progression of type 1 and type 2 diabetes in children and adults
Diabetes is a common chronic metabolic disease with complex causes and pathogenesis. As an immunomodulator, vitamin D has recently become a research hotspot in the occurrence and development of diabetes and its complications. Many studies have shown that vitamin D can reduce the occurrence of diabet...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-04-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2024.1360525/full |
| _version_ | 1797219312592748544 |
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| author | Candong Li Jiaowen Fu Yipeng Ye Junsen Li Yangli He Tuanyu Fang |
| author_facet | Candong Li Jiaowen Fu Yipeng Ye Junsen Li Yangli He Tuanyu Fang |
| author_sort | Candong Li |
| collection | DOAJ |
| description | Diabetes is a common chronic metabolic disease with complex causes and pathogenesis. As an immunomodulator, vitamin D has recently become a research hotspot in the occurrence and development of diabetes and its complications. Many studies have shown that vitamin D can reduce the occurrence of diabetes and delay the progression of diabetes complications, and vitamin D can reduce oxidative stress, inhibit iron apoptosis, promote Ca2+ influx, promote insulin secretion, and reduce insulin resistance. Therefore, the prevention and correction of vitamin D deficiency is very necessary for diabetic patients, but further research is needed to confirm what serum levels of vitamin D3 are maintained in the body. This article provides a brief review of the relationship between vitamin D and diabetes, including its acute and chronic complications. |
| first_indexed | 2024-04-24T12:31:39Z |
| format | Article |
| id | doaj.art-5113022224af442dbdbbe558c898e6ac |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-24T12:31:39Z |
| publishDate | 2024-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-5113022224af442dbdbbe558c898e6ac2024-04-08T04:24:23ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922024-04-011510.3389/fendo.2024.13605251360525The impact of vitamin D on the etiopathogenesis and the progression of type 1 and type 2 diabetes in children and adultsCandong Li0Jiaowen Fu1Yipeng Ye2Junsen Li3Yangli He4Tuanyu Fang5Department of Endocrine, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, ChinaDepartment of Endocrine, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, ChinaDepartment of Endocrine, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, ChinaDepartment of Endocrine, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, ChinaDepartment of Health Care Centre, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, ChinaDepartment of Endocrine, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, ChinaDiabetes is a common chronic metabolic disease with complex causes and pathogenesis. As an immunomodulator, vitamin D has recently become a research hotspot in the occurrence and development of diabetes and its complications. Many studies have shown that vitamin D can reduce the occurrence of diabetes and delay the progression of diabetes complications, and vitamin D can reduce oxidative stress, inhibit iron apoptosis, promote Ca2+ influx, promote insulin secretion, and reduce insulin resistance. Therefore, the prevention and correction of vitamin D deficiency is very necessary for diabetic patients, but further research is needed to confirm what serum levels of vitamin D3 are maintained in the body. This article provides a brief review of the relationship between vitamin D and diabetes, including its acute and chronic complications.https://www.frontiersin.org/articles/10.3389/fendo.2024.1360525/fullvitamin Ddiabetes mellitusdiabetic complicationsinsulin resistancepathogenesis |
| spellingShingle | Candong Li Jiaowen Fu Yipeng Ye Junsen Li Yangli He Tuanyu Fang The impact of vitamin D on the etiopathogenesis and the progression of type 1 and type 2 diabetes in children and adults Frontiers in Endocrinology vitamin D diabetes mellitus diabetic complications insulin resistance pathogenesis |
| title | The impact of vitamin D on the etiopathogenesis and the progression of type 1 and type 2 diabetes in children and adults |
| title_full | The impact of vitamin D on the etiopathogenesis and the progression of type 1 and type 2 diabetes in children and adults |
| title_fullStr | The impact of vitamin D on the etiopathogenesis and the progression of type 1 and type 2 diabetes in children and adults |
| title_full_unstemmed | The impact of vitamin D on the etiopathogenesis and the progression of type 1 and type 2 diabetes in children and adults |
| title_short | The impact of vitamin D on the etiopathogenesis and the progression of type 1 and type 2 diabetes in children and adults |
| title_sort | impact of vitamin d on the etiopathogenesis and the progression of type 1 and type 2 diabetes in children and adults |
| topic | vitamin D diabetes mellitus diabetic complications insulin resistance pathogenesis |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2024.1360525/full |
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