Recent five-year progress in the impact of gut microbiota on vaccination and possible mechanisms
Abstract Vaccine is the most effective way to prevent the spread of communicable diseases, but the immune response induced by it varies greatly between individuals and populations in different regions of the world. Current studies have identified the composition and function of the gut microbiota as...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | Gut Pathogens |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13099-023-00547-y |
| _version_ | 1797778829870104576 |
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| author | Biqing Huang Jianwei Wang Lanjuan Li |
| author_facet | Biqing Huang Jianwei Wang Lanjuan Li |
| author_sort | Biqing Huang |
| collection | DOAJ |
| description | Abstract Vaccine is the most effective way to prevent the spread of communicable diseases, but the immune response induced by it varies greatly between individuals and populations in different regions of the world. Current studies have identified the composition and function of the gut microbiota as key factors in modulating the immune response to vaccination. This article mainly reviews the differences in gut microbiota among different groups of vaccinated people and animals, explores the possible mechanism of vaccine immunity affected by gut microbiota, and reviews the strategies for targeting gut microbiota to improve vaccine efficacy. |
| first_indexed | 2024-03-12T23:23:11Z |
| format | Article |
| id | doaj.art-511435506fcc478bbcbd88264a326908 |
| institution | Directory Open Access Journal |
| issn | 1757-4749 |
| language | English |
| last_indexed | 2024-03-12T23:23:11Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Gut Pathogens |
| spelling | doaj.art-511435506fcc478bbcbd88264a3269082023-07-16T11:18:12ZengBMCGut Pathogens1757-47492023-06-011511710.1186/s13099-023-00547-yRecent five-year progress in the impact of gut microbiota on vaccination and possible mechanismsBiqing Huang0Jianwei Wang1Lanjuan Li2State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University school of medicineNHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences & Peking Union Medical CollegeState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University school of medicineAbstract Vaccine is the most effective way to prevent the spread of communicable diseases, but the immune response induced by it varies greatly between individuals and populations in different regions of the world. Current studies have identified the composition and function of the gut microbiota as key factors in modulating the immune response to vaccination. This article mainly reviews the differences in gut microbiota among different groups of vaccinated people and animals, explores the possible mechanism of vaccine immunity affected by gut microbiota, and reviews the strategies for targeting gut microbiota to improve vaccine efficacy.https://doi.org/10.1186/s13099-023-00547-yGut microbiotaVaccineImmune efficacy |
| spellingShingle | Biqing Huang Jianwei Wang Lanjuan Li Recent five-year progress in the impact of gut microbiota on vaccination and possible mechanisms Gut Pathogens Gut microbiota Vaccine Immune efficacy |
| title | Recent five-year progress in the impact of gut microbiota on vaccination and possible mechanisms |
| title_full | Recent five-year progress in the impact of gut microbiota on vaccination and possible mechanisms |
| title_fullStr | Recent five-year progress in the impact of gut microbiota on vaccination and possible mechanisms |
| title_full_unstemmed | Recent five-year progress in the impact of gut microbiota on vaccination and possible mechanisms |
| title_short | Recent five-year progress in the impact of gut microbiota on vaccination and possible mechanisms |
| title_sort | recent five year progress in the impact of gut microbiota on vaccination and possible mechanisms |
| topic | Gut microbiota Vaccine Immune efficacy |
| url | https://doi.org/10.1186/s13099-023-00547-y |
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