Association of cataract extraction and the risk of dementia—A systematic review and meta-analysis
ObjectivesThis research aims to investigate if cataract extraction lowers the risk of all-cause dementia.MethodsOriginal literature on cataract surgery associated with all-cause dementia as of November 27, 2022, was searched in several commonly used databases. Manual review was used to include eligi...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Aging Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1168449/full |
| _version_ | 1827941512624734208 |
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| author | Qiao Zhang Yuan Ju Wei Zheng Lulu Xie Xi Wang Huanhuan Ren Zhipeng Chen Xingtong Liu Xiaolin Bai Ruile Fan |
| author_facet | Qiao Zhang Yuan Ju Wei Zheng Lulu Xie Xi Wang Huanhuan Ren Zhipeng Chen Xingtong Liu Xiaolin Bai Ruile Fan |
| author_sort | Qiao Zhang |
| collection | DOAJ |
| description | ObjectivesThis research aims to investigate if cataract extraction lowers the risk of all-cause dementia.MethodsOriginal literature on cataract surgery associated with all-cause dementia as of November 27, 2022, was searched in several commonly used databases. Manual review was used to include eligible studies. Stata software (version 16) was used to perform statistical analysis on pertinent data. Publication bias can be precisely evaluated using funnel plots and Egger's test.ResultsIn the meta-analysis of 4 cohort studies with 245,299 participants. Pooled analysis indicated that cataract surgery was linked to a lower incidence of all-cause dementia (OR = 0.77, 95%CI: 0.66–0.89; I2= 54.7%; P < 0.001). Cataract surgery was linked to a lower risk of AD (OR = 0.60, 95%CI: 0.35–1.02; I2= 60.2%; P < 0.001).ConclusionsCataract surgery is linked to a lower incidence of all-cause dementia and Alzheimer's disease. A cataract is a reversible visual impairment. Cataract surgery may be a protective factor against the onset of all-cause dementia and can reduce the economic and family burden caused by all-cause dementia worldwide. Given the restricted pool of included studies, our findings necessitate meticulous interpretation.Systematic review registrationhttp://www.crd.york.ac.uk/prospero retrieve registration details by searching CRD4202379371. |
| first_indexed | 2024-03-13T09:38:18Z |
| format | Article |
| id | doaj.art-5114e9eb358346e6ae6c6bea41456c41 |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-03-13T09:38:18Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-5114e9eb358346e6ae6c6bea41456c412023-05-25T05:00:49ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652023-05-011510.3389/fnagi.2023.11684491168449Association of cataract extraction and the risk of dementia—A systematic review and meta-analysisQiao Zhang0Yuan Ju1Wei Zheng2Lulu Xie3Xi Wang4Huanhuan Ren5Zhipeng Chen6Xingtong Liu7Xiaolin Bai8Ruile Fan9College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, ChinaDepartment of Ophthalmology, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, ChinaDepartment of Ophthalmology, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, ChinaCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, ChinaCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, ChinaCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, ChinaCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, ChinaCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, ChinaCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, ChinaCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, ChinaObjectivesThis research aims to investigate if cataract extraction lowers the risk of all-cause dementia.MethodsOriginal literature on cataract surgery associated with all-cause dementia as of November 27, 2022, was searched in several commonly used databases. Manual review was used to include eligible studies. Stata software (version 16) was used to perform statistical analysis on pertinent data. Publication bias can be precisely evaluated using funnel plots and Egger's test.ResultsIn the meta-analysis of 4 cohort studies with 245,299 participants. Pooled analysis indicated that cataract surgery was linked to a lower incidence of all-cause dementia (OR = 0.77, 95%CI: 0.66–0.89; I2= 54.7%; P < 0.001). Cataract surgery was linked to a lower risk of AD (OR = 0.60, 95%CI: 0.35–1.02; I2= 60.2%; P < 0.001).ConclusionsCataract surgery is linked to a lower incidence of all-cause dementia and Alzheimer's disease. A cataract is a reversible visual impairment. Cataract surgery may be a protective factor against the onset of all-cause dementia and can reduce the economic and family burden caused by all-cause dementia worldwide. Given the restricted pool of included studies, our findings necessitate meticulous interpretation.Systematic review registrationhttp://www.crd.york.ac.uk/prospero retrieve registration details by searching CRD4202379371.https://www.frontiersin.org/articles/10.3389/fnagi.2023.1168449/fullcataractdementiaAlzheimer's diseasemeta-analysiscohort study |
| spellingShingle | Qiao Zhang Yuan Ju Wei Zheng Lulu Xie Xi Wang Huanhuan Ren Zhipeng Chen Xingtong Liu Xiaolin Bai Ruile Fan Association of cataract extraction and the risk of dementia—A systematic review and meta-analysis Frontiers in Aging Neuroscience cataract dementia Alzheimer's disease meta-analysis cohort study |
| title | Association of cataract extraction and the risk of dementia—A systematic review and meta-analysis |
| title_full | Association of cataract extraction and the risk of dementia—A systematic review and meta-analysis |
| title_fullStr | Association of cataract extraction and the risk of dementia—A systematic review and meta-analysis |
| title_full_unstemmed | Association of cataract extraction and the risk of dementia—A systematic review and meta-analysis |
| title_short | Association of cataract extraction and the risk of dementia—A systematic review and meta-analysis |
| title_sort | association of cataract extraction and the risk of dementia a systematic review and meta analysis |
| topic | cataract dementia Alzheimer's disease meta-analysis cohort study |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1168449/full |
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