Determinants of uncontrolled allergic rhinitis in Kinshasa hospitals
ObjectiveTo identify the determinants of uncontrolled allergic rhinitis (UCAR) in a hospital setting in Kinshasa, Democratic Republic of Congo.MethodsHospital-based cross-sectional study of 153 patients with allergic rhinitis (AR). The diagnosis of AR was based on clinical grounds according to the A...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Allergy |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/falgy.2023.1138537/full |
| _version_ | 1797866160450961408 |
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| author | Patricia K. Kakobo Hilaire K. Kalala Joseph K. Kelekele Paulin B. Mutombo Dieudonné T. Nyembue Peter W. Hellings Peter W. Hellings Peter W. Hellings Jean-Marie N. Kayembe |
| author_facet | Patricia K. Kakobo Hilaire K. Kalala Joseph K. Kelekele Paulin B. Mutombo Dieudonné T. Nyembue Peter W. Hellings Peter W. Hellings Peter W. Hellings Jean-Marie N. Kayembe |
| author_sort | Patricia K. Kakobo |
| collection | DOAJ |
| description | ObjectiveTo identify the determinants of uncontrolled allergic rhinitis (UCAR) in a hospital setting in Kinshasa, Democratic Republic of Congo.MethodsHospital-based cross-sectional study of 153 patients with allergic rhinitis (AR). The diagnosis of AR was based on clinical grounds according to the Allergic Rhinitis and its Impact on Asthma (ARIA) criteria. Categorization into controlled AR (CAR) and UCAR was based on the visual analog scale (VAS with cut off point of 5). Binary logistic regression was used to identify factors associated with UCAR.ResultsPatients with UCAR (60.1%) proportionally outnumbered those with CAR (39.9%). There were significantly more patients younger than 30 years of age among patients with UCAR. Factors significantly associated with UCAR were age below 30 years (OR = 3.31; 95% CI: 1.49–7.36; p = 0.003), low serum vitamin D level (OR = 3.86; 95% CI: 1.72–8.68; p = 0.001), persistent form (OR = 3.11; 95% CI: 1.39–6.98; p = 0.006) and moderate to severe form of AR (OR = 4.31; 95% CI: 1.77–10.49; p = 0.001).ConclusionsFactors associated with UCAR in this study population were younger age less than 30 years, low vitamin D level, and persistent as well as moderate to severe AR. Further studies are needed to elucidate the underlying mechanisms favoring the occurrence of these factors. |
| first_indexed | 2024-04-09T23:19:34Z |
| format | Article |
| id | doaj.art-5118e93dd281489aba335df92baabb50 |
| institution | Directory Open Access Journal |
| issn | 2673-6101 |
| language | English |
| last_indexed | 2024-04-09T23:19:34Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Allergy |
| spelling | doaj.art-5118e93dd281489aba335df92baabb502023-03-22T04:29:04ZengFrontiers Media S.A.Frontiers in Allergy2673-61012023-03-01410.3389/falgy.2023.11385371138537Determinants of uncontrolled allergic rhinitis in Kinshasa hospitalsPatricia K. Kakobo0Hilaire K. Kalala1Joseph K. Kelekele2Paulin B. Mutombo3Dieudonné T. Nyembue4Peter W. Hellings5Peter W. Hellings6Peter W. Hellings7Jean-Marie N. Kayembe8Department of Otorhinolaryngology, University of Kinshasa, Kinshasa, Democratic Republic of CongoDepartment of Otorhinolaryngology, University of Kinshasa, Kinshasa, Democratic Republic of CongoOphthalmology Department, University of Kinshasa, Kinshasa, Democratic Republic of CongoSchool of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of CongoDepartment of Otorhinolaryngology, University of Kinshasa, Kinshasa, Democratic Republic of CongoDepartment of Otorhinolaryngology-Head and Nose Surgery, University Hospital of Leuven, Leuven, BelgiumDepartment of Otorhinolaryngology, Academic Medical Center, University of Amsterdam, Amsterdam, NetherlandsUpper Airways Research Laboratory, University of Ghent, Ghent, BelgiumDepartment of Pneumology, University of Kinshasa, Kinshasa, Democratic Republic of CongoObjectiveTo identify the determinants of uncontrolled allergic rhinitis (UCAR) in a hospital setting in Kinshasa, Democratic Republic of Congo.MethodsHospital-based cross-sectional study of 153 patients with allergic rhinitis (AR). The diagnosis of AR was based on clinical grounds according to the Allergic Rhinitis and its Impact on Asthma (ARIA) criteria. Categorization into controlled AR (CAR) and UCAR was based on the visual analog scale (VAS with cut off point of 5). Binary logistic regression was used to identify factors associated with UCAR.ResultsPatients with UCAR (60.1%) proportionally outnumbered those with CAR (39.9%). There were significantly more patients younger than 30 years of age among patients with UCAR. Factors significantly associated with UCAR were age below 30 years (OR = 3.31; 95% CI: 1.49–7.36; p = 0.003), low serum vitamin D level (OR = 3.86; 95% CI: 1.72–8.68; p = 0.001), persistent form (OR = 3.11; 95% CI: 1.39–6.98; p = 0.006) and moderate to severe form of AR (OR = 4.31; 95% CI: 1.77–10.49; p = 0.001).ConclusionsFactors associated with UCAR in this study population were younger age less than 30 years, low vitamin D level, and persistent as well as moderate to severe AR. Further studies are needed to elucidate the underlying mechanisms favoring the occurrence of these factors.https://www.frontiersin.org/articles/10.3389/falgy.2023.1138537/fulluncontrolled allergic rhinitisvitamin dpersistent formmoderate to severe formKinshasa |
| spellingShingle | Patricia K. Kakobo Hilaire K. Kalala Joseph K. Kelekele Paulin B. Mutombo Dieudonné T. Nyembue Peter W. Hellings Peter W. Hellings Peter W. Hellings Jean-Marie N. Kayembe Determinants of uncontrolled allergic rhinitis in Kinshasa hospitals Frontiers in Allergy uncontrolled allergic rhinitis vitamin d persistent form moderate to severe form Kinshasa |
| title | Determinants of uncontrolled allergic rhinitis in Kinshasa hospitals |
| title_full | Determinants of uncontrolled allergic rhinitis in Kinshasa hospitals |
| title_fullStr | Determinants of uncontrolled allergic rhinitis in Kinshasa hospitals |
| title_full_unstemmed | Determinants of uncontrolled allergic rhinitis in Kinshasa hospitals |
| title_short | Determinants of uncontrolled allergic rhinitis in Kinshasa hospitals |
| title_sort | determinants of uncontrolled allergic rhinitis in kinshasa hospitals |
| topic | uncontrolled allergic rhinitis vitamin d persistent form moderate to severe form Kinshasa |
| url | https://www.frontiersin.org/articles/10.3389/falgy.2023.1138537/full |
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