Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in Mice.

Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in Mice.

<h4>Background</h4>Various transient receptor potential (TRP) channels in sensory neurons contribute to the transduction of mechanical stimuli in the colon. Recently, even the cold-sensing menthol receptor TRPM(melastatin)8 was suggested to be involved in murine colonic mechano-nocicepti...

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Bibliographic Details
Main Authors: Sonja M Mueller-Tribbensee, Manoj Karna, Mohammad Khalil, Markus F Neurath, Peter W Reeh, Matthias A Engel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0128242

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