Hypouricemic Effects of Extracts From Agrocybe aegerita on Hyperuricemia Mice and Virtual Prediction of Bioactives by Molecular Docking

Hypouricemic Effects of Extracts From Agrocybe aegerita on Hyperuricemia Mice and Virtual Prediction of Bioactives by Molecular Docking

Agrocybe aegerita has long been utilized for promoting diuresis in traditional Chinese medicine (TCM) with a close correlation to hypouricemia. Ethanol (AAE) and water (AAW) extracts of the compound led to a remarkable decrease in serum uric acid levels (SUA) in hyperuricemia mice, approaching that...

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Bibliographic Details
Main Authors: Tianqiao Yong, Shaodan Chen, Yizhen Xie, Ou Shuai, Xiangmin Li, Diling Chen, Jiyan Su, Chunwei Jiao, Yalei Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
Agrocybe aegerita
hyperuricemia
xanthine oxidase
bioactives
virtual screening
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00498/full

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