Virilizing Ovarian Steroid Cell Tumor: A Rare Case

Ovarian steroid cell tumours are fewer than 5 percent of sex-cord stromal tumours and 0.1% of all ovarian tumours. The average age at diagnosis is the mid-20s, but patients can present at virtually any age. We present a case of 38-year-old multipara with history of secondary amenorrhea, clinical s...

Full description

Bibliographic Details
Main Authors: Aishwarya Bettegowda, Nagarathnamma Rangaiah, Nagendra Prasad, Savitha Channa Veeregowda
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2015-09-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/6435/14301_CE(RA1)_F(T)_PF1(AGAK)_PFA(AK)_PF2(PAG).pdf
Description
Summary:Ovarian steroid cell tumours are fewer than 5 percent of sex-cord stromal tumours and 0.1% of all ovarian tumours. The average age at diagnosis is the mid-20s, but patients can present at virtually any age. We present a case of 38-year-old multipara with history of secondary amenorrhea, clinical signs & symptoms of virilization developed over the past 5 years. With elevated (115ng/dL) serum testosterone level and radiological findings of a left adnexal solid mass; the patient was suspected to have a virilizing tumour of left ovary. Laparoscopic left salpingo-oophorectomy was performed. Histopathology revealed tumour cells in small nests with vacuolated to eosinophilic cytoplasm with nuclear atypia completely replacing the ovarian tissue suggestive of steroid cell tumour (NOS) of ovary. The patient was discharged and advised for follow up with serum testosterone levels after 3 weeks.
ISSN:2249-782X
0973-709X