Virilizing Ovarian Steroid Cell Tumor: A Rare Case

Ovarian steroid cell tumours are fewer than 5 percent of sex-cord stromal tumours and 0.1% of all ovarian tumours. The average age at diagnosis is the mid-20s, but patients can present at virtually any age. We present a case of 38-year-old multipara with history of secondary amenorrhea, clinical s...

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Main Authors: Aishwarya Bettegowda, Nagarathnamma Rangaiah, Nagendra Prasad, Savitha Channa Veeregowda
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2015-09-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/6435/14301_CE(RA1)_F(T)_PF1(AGAK)_PFA(AK)_PF2(PAG).pdf
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author Aishwarya Bettegowda
Nagarathnamma Rangaiah
Nagendra Prasad
Savitha Channa Veeregowda
author_facet Aishwarya Bettegowda
Nagarathnamma Rangaiah
Nagendra Prasad
Savitha Channa Veeregowda
author_sort Aishwarya Bettegowda
collection DOAJ
description Ovarian steroid cell tumours are fewer than 5 percent of sex-cord stromal tumours and 0.1% of all ovarian tumours. The average age at diagnosis is the mid-20s, but patients can present at virtually any age. We present a case of 38-year-old multipara with history of secondary amenorrhea, clinical signs & symptoms of virilization developed over the past 5 years. With elevated (115ng/dL) serum testosterone level and radiological findings of a left adnexal solid mass; the patient was suspected to have a virilizing tumour of left ovary. Laparoscopic left salpingo-oophorectomy was performed. Histopathology revealed tumour cells in small nests with vacuolated to eosinophilic cytoplasm with nuclear atypia completely replacing the ovarian tissue suggestive of steroid cell tumour (NOS) of ovary. The patient was discharged and advised for follow up with serum testosterone levels after 3 weeks.
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spelling doaj.art-511ee3d6087d4da691f9847c07f329262022-12-22T01:43:34ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-09-0199QD05QD0610.7860/JCDR/2015/14301.6435Virilizing Ovarian Steroid Cell Tumor: A Rare CaseAishwarya Bettegowda0Nagarathnamma Rangaiah1Nagendra Prasad2Savitha Channa Veeregowda3Post-Graduate, Department of Obstetrics and Gynaecology, Rajarajeswari Medical College, Bangalore, Karnataka, India.Professor & HoD, Department of Obstetrics and Gynaecology, Rajarajeswari Medical College, Bangalore, Karnataka, India.Associate Professor, Department of Obstetrics and Gynaecology, Rajarajeswari Medical College, Bangalore, Karnataka, India.Assistant Professor, Department of Obstetrics and Gynaecology, Rajarajeswari Medical College, Bangalore, Karnataka, India.Ovarian steroid cell tumours are fewer than 5 percent of sex-cord stromal tumours and 0.1% of all ovarian tumours. The average age at diagnosis is the mid-20s, but patients can present at virtually any age. We present a case of 38-year-old multipara with history of secondary amenorrhea, clinical signs & symptoms of virilization developed over the past 5 years. With elevated (115ng/dL) serum testosterone level and radiological findings of a left adnexal solid mass; the patient was suspected to have a virilizing tumour of left ovary. Laparoscopic left salpingo-oophorectomy was performed. Histopathology revealed tumour cells in small nests with vacuolated to eosinophilic cytoplasm with nuclear atypia completely replacing the ovarian tissue suggestive of steroid cell tumour (NOS) of ovary. The patient was discharged and advised for follow up with serum testosterone levels after 3 weeks.https://jcdr.net/articles/PDF/6435/14301_CE(RA1)_F(T)_PF1(AGAK)_PFA(AK)_PF2(PAG).pdfserum testosteronesex-cord stromal tumoursvirilizing tumour
spellingShingle Aishwarya Bettegowda
Nagarathnamma Rangaiah
Nagendra Prasad
Savitha Channa Veeregowda
Virilizing Ovarian Steroid Cell Tumor: A Rare Case
Journal of Clinical and Diagnostic Research
serum testosterone
sex-cord stromal tumours
virilizing tumour
title Virilizing Ovarian Steroid Cell Tumor: A Rare Case
title_full Virilizing Ovarian Steroid Cell Tumor: A Rare Case
title_fullStr Virilizing Ovarian Steroid Cell Tumor: A Rare Case
title_full_unstemmed Virilizing Ovarian Steroid Cell Tumor: A Rare Case
title_short Virilizing Ovarian Steroid Cell Tumor: A Rare Case
title_sort virilizing ovarian steroid cell tumor a rare case
topic serum testosterone
sex-cord stromal tumours
virilizing tumour
url https://jcdr.net/articles/PDF/6435/14301_CE(RA1)_F(T)_PF1(AGAK)_PFA(AK)_PF2(PAG).pdf
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