Assessing Quality-of-Life of Patients Taking Mirabegron for Overactive Bladder
Christina Shaw,1 William Gibson2 1Division of Geriatric Medicine, University of British Columbia, Vancouver, British Columbia, Canada; 2Division of Geriatric Medicine, University of Alberta, Edmonton, Alberta, CanadaCorrespondence: William Gibson, Division of Geriatric Medicine, University of Albert...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2023-01-01
|
| Series: | Therapeutics and Clinical Risk Management |
| Subjects: | |
| Online Access: | https://www.dovepress.com/assessing-quality-of-life-of-patients-taking-mirabegron-for-overactive-peer-reviewed-fulltext-article-TCRM |
| _version_ | 1797956517109956608 |
|---|---|
| author | Shaw C Gibson W |
| author_facet | Shaw C Gibson W |
| author_sort | Shaw C |
| collection | DOAJ |
| description | Christina Shaw,1 William Gibson2 1Division of Geriatric Medicine, University of British Columbia, Vancouver, British Columbia, Canada; 2Division of Geriatric Medicine, University of Alberta, Edmonton, Alberta, CanadaCorrespondence: William Gibson, Division of Geriatric Medicine, University of Alberta, 1-198 Clinical Sciences Building, 11350 83 Ave NW, Edmonton, Alberta, T6E 2K4, Canada, Tel +1 780 248 1969, Fax +1 780 492 2874, Email wgibson@ualberta.caAbstract: Lower urinary tract symptoms (LUTS), including urgency, frequency, and urgency incontinence, are highly prevalent in the general population and increase in prevalence with increasing age. All LUTS, but notable urgency and urgency incontinence, are associated with negative impact on quality-of-life (QoL), with multiple aspects of QoL affected. Urgency and urgency incontinence are most commonly caused by overactive bladder (OAB), the clinical syndrome of urinary urgency, usually accompanied by increased daytime frequency and/or nocturia in the absence of infection or other obvious etiology, which may be treated with conservative and lifestyle interventions, bladder antimuscarinic drugs, and, more recently, by mirabegron, a β 3 agonist. This narrative review describes the impact of OAB on QoL, quantifies this impact, and outlines the evidence for the use of mirabegron in the treatment of, and improvement in QoL in, people with OAB.Keywords: lower urinary tract symptoms, incontinence, quality-of-life, health-related quality-of-life, mirabegron |
| first_indexed | 2024-04-10T23:51:13Z |
| format | Article |
| id | doaj.art-511f1eea89f34cbb84d90e8a89a89a72 |
| institution | Directory Open Access Journal |
| issn | 1178-203X |
| language | English |
| last_indexed | 2024-04-10T23:51:13Z |
| publishDate | 2023-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Therapeutics and Clinical Risk Management |
| spelling | doaj.art-511f1eea89f34cbb84d90e8a89a89a722023-01-10T18:24:32ZengDove Medical PressTherapeutics and Clinical Risk Management1178-203X2023-01-01Volume 19273380914Assessing Quality-of-Life of Patients Taking Mirabegron for Overactive BladderShaw CGibson WChristina Shaw,1 William Gibson2 1Division of Geriatric Medicine, University of British Columbia, Vancouver, British Columbia, Canada; 2Division of Geriatric Medicine, University of Alberta, Edmonton, Alberta, CanadaCorrespondence: William Gibson, Division of Geriatric Medicine, University of Alberta, 1-198 Clinical Sciences Building, 11350 83 Ave NW, Edmonton, Alberta, T6E 2K4, Canada, Tel +1 780 248 1969, Fax +1 780 492 2874, Email wgibson@ualberta.caAbstract: Lower urinary tract symptoms (LUTS), including urgency, frequency, and urgency incontinence, are highly prevalent in the general population and increase in prevalence with increasing age. All LUTS, but notable urgency and urgency incontinence, are associated with negative impact on quality-of-life (QoL), with multiple aspects of QoL affected. Urgency and urgency incontinence are most commonly caused by overactive bladder (OAB), the clinical syndrome of urinary urgency, usually accompanied by increased daytime frequency and/or nocturia in the absence of infection or other obvious etiology, which may be treated with conservative and lifestyle interventions, bladder antimuscarinic drugs, and, more recently, by mirabegron, a β 3 agonist. This narrative review describes the impact of OAB on QoL, quantifies this impact, and outlines the evidence for the use of mirabegron in the treatment of, and improvement in QoL in, people with OAB.Keywords: lower urinary tract symptoms, incontinence, quality-of-life, health-related quality-of-life, mirabegronhttps://www.dovepress.com/assessing-quality-of-life-of-patients-taking-mirabegron-for-overactive-peer-reviewed-fulltext-article-TCRMlower urinary tract symptomsincontinencequality of lifehealth-related quality of lifemirabegron |
| spellingShingle | Shaw C Gibson W Assessing Quality-of-Life of Patients Taking Mirabegron for Overactive Bladder Therapeutics and Clinical Risk Management lower urinary tract symptoms incontinence quality of life health-related quality of life mirabegron |
| title | Assessing Quality-of-Life of Patients Taking Mirabegron for Overactive Bladder |
| title_full | Assessing Quality-of-Life of Patients Taking Mirabegron for Overactive Bladder |
| title_fullStr | Assessing Quality-of-Life of Patients Taking Mirabegron for Overactive Bladder |
| title_full_unstemmed | Assessing Quality-of-Life of Patients Taking Mirabegron for Overactive Bladder |
| title_short | Assessing Quality-of-Life of Patients Taking Mirabegron for Overactive Bladder |
| title_sort | assessing quality of life of patients taking mirabegron for overactive bladder |
| topic | lower urinary tract symptoms incontinence quality of life health-related quality of life mirabegron |
| url | https://www.dovepress.com/assessing-quality-of-life-of-patients-taking-mirabegron-for-overactive-peer-reviewed-fulltext-article-TCRM |
| work_keys_str_mv | AT shawc assessingqualityoflifeofpatientstakingmirabegronforoveractivebladder AT gibsonw assessingqualityoflifeofpatientstakingmirabegronforoveractivebladder |