Cervical Primitive Neuroectodermal Tumor in an Adult: Case Report and Literature Review*
Introduction Primitive neuroectodermal tumors are rare neoplasms of the central nervous system that occur in children, with few reports in adults. These tumors are found most often in the cerebral hemispheres, with spinal cord disorders being rare. Case Report A 71-year-old man with motor...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações Ltda.
2022-06-01
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| Series: | Brazilian Neurosurgery |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1742709 |
| _version_ | 1818533249842937856 |
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| author | Guilherme dos Santos de Alencar Maria Eduarda Turczyn De Lucca Felipe Antonio Torres Mazzo Milena Massumi Konozoe Eduardo Talib Bacchi Jaouhari Rodrigo Leite de Morais Carlos Eliseu Barcelos Rosângela Stadnick Lauth de Almeida Torres |
| author_facet | Guilherme dos Santos de Alencar Maria Eduarda Turczyn De Lucca Felipe Antonio Torres Mazzo Milena Massumi Konozoe Eduardo Talib Bacchi Jaouhari Rodrigo Leite de Morais Carlos Eliseu Barcelos Rosângela Stadnick Lauth de Almeida Torres |
| author_sort | Guilherme dos Santos de Alencar |
| collection | DOAJ |
| description | Introduction Primitive neuroectodermal tumors are rare neoplasms of the central nervous system that occur in children, with few reports in adults. These tumors are found most often in the cerebral hemispheres, with spinal cord disorders being rare.
Case Report A 71-year-old man with motor and sensory deficits in the upper limbs, cervical pain, and urinary incontinence presented to the Neurosurgery Service. The physical examination revealed grade-III motor strength on the right side, grade IV- on the left upper limb, and grade IV+ on the left lower limb. A magnetic resonance imaging scan showed an expansive intramedullary lesion with a C3-C4 epicenter. Spinal decompression, lesional biopsy, and adjuvant radiotherapy were performed. The anatomopathological report showed a primitive neuroectodermal tumor. After a new treatment with adjuvant radiotherapy (20 × 1.8 Gy in the skull and neuroaxis and 5 × 1.8 Gy in tumor boost), the patient progressed without recurrence.
Conclusion Since the characteristics of the tumor are similar to those of medulloblastoma, it is necessary to expand the studies on these lesions, to better understand their pathophysiology and list better diagnostic and therapeutic methods, in addition to those already available. |
| first_indexed | 2024-12-11T17:56:12Z |
| format | Article |
| id | doaj.art-5122692e8c3c4689a00ed0b197c6171d |
| institution | Directory Open Access Journal |
| issn | 0103-5355 2359-5922 |
| language | English |
| last_indexed | 2024-12-11T17:56:12Z |
| publishDate | 2022-06-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | Brazilian Neurosurgery |
| spelling | doaj.art-5122692e8c3c4689a00ed0b197c6171d2022-12-22T00:56:04ZengThieme Revinter Publicações Ltda.Brazilian Neurosurgery0103-53552359-59222022-06-014102e187e19110.1055/s-0042-1742709Cervical Primitive Neuroectodermal Tumor in an Adult: Case Report and Literature Review*Guilherme dos Santos de Alencar0Maria Eduarda Turczyn De Lucca1Felipe Antonio Torres Mazzo2Milena Massumi Konozoe3Eduardo Talib Bacchi Jaouhari4Rodrigo Leite de Morais5Carlos Eliseu Barcelos6Rosângela Stadnick Lauth de Almeida Torres7Department of Neurosurgery, Curso de Medicina, Universidade Federal do Paraná (UFPR), Curitiba, PR, BrazilUniversidade Positivo (UP), Curitiba, PR, BrazilMedicine Program, Pontifícia Universidade Católica do Paraná (PUCPR), Curitiba, PR, BrazilDepartment of Pathology, Hospital Erasto Gaertner, Curitiba, PR, BrazilDepartment of Neurosurgery, Hospital Erasto Gaertner, Curitiba, PR, BrazilDepartment of Neurosurgery, Hospital Erasto Gaertner, Curitiba, PR, BrazilDepartment of Neurosurgery, Hospital Erasto Gaertner, Curitiba, PR, BrazilDepartment of Pharmaceutical Sciences, Faculdade de Farmácia, Universidade Positivo (UP), Curitiba, PR, BrazilIntroduction Primitive neuroectodermal tumors are rare neoplasms of the central nervous system that occur in children, with few reports in adults. These tumors are found most often in the cerebral hemispheres, with spinal cord disorders being rare. Case Report A 71-year-old man with motor and sensory deficits in the upper limbs, cervical pain, and urinary incontinence presented to the Neurosurgery Service. The physical examination revealed grade-III motor strength on the right side, grade IV- on the left upper limb, and grade IV+ on the left lower limb. A magnetic resonance imaging scan showed an expansive intramedullary lesion with a C3-C4 epicenter. Spinal decompression, lesional biopsy, and adjuvant radiotherapy were performed. The anatomopathological report showed a primitive neuroectodermal tumor. After a new treatment with adjuvant radiotherapy (20 × 1.8 Gy in the skull and neuroaxis and 5 × 1.8 Gy in tumor boost), the patient progressed without recurrence. Conclusion Since the characteristics of the tumor are similar to those of medulloblastoma, it is necessary to expand the studies on these lesions, to better understand their pathophysiology and list better diagnostic and therapeutic methods, in addition to those already available.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1742709primitive neuroectodermal tumorsadultmedulloblastoma |
| spellingShingle | Guilherme dos Santos de Alencar Maria Eduarda Turczyn De Lucca Felipe Antonio Torres Mazzo Milena Massumi Konozoe Eduardo Talib Bacchi Jaouhari Rodrigo Leite de Morais Carlos Eliseu Barcelos Rosângela Stadnick Lauth de Almeida Torres Cervical Primitive Neuroectodermal Tumor in an Adult: Case Report and Literature Review* Brazilian Neurosurgery primitive neuroectodermal tumors adult medulloblastoma |
| title | Cervical Primitive Neuroectodermal Tumor in an Adult: Case Report and Literature Review* |
| title_full | Cervical Primitive Neuroectodermal Tumor in an Adult: Case Report and Literature Review* |
| title_fullStr | Cervical Primitive Neuroectodermal Tumor in an Adult: Case Report and Literature Review* |
| title_full_unstemmed | Cervical Primitive Neuroectodermal Tumor in an Adult: Case Report and Literature Review* |
| title_short | Cervical Primitive Neuroectodermal Tumor in an Adult: Case Report and Literature Review* |
| title_sort | cervical primitive neuroectodermal tumor in an adult case report and literature review |
| topic | primitive neuroectodermal tumors adult medulloblastoma |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1742709 |
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