Modern methods for radionuclide diagnosis of tumors and non-tumor pathologies of the brain
The review analyzes the global experience in the application of nuclear medicine techniques for diagnosis of tumors and non-tumor pathologies of the brain. The main groups of radiopharmaceuticals currently used for imaging of malignant brain tumors and diagnosis of cognitive impairments and neurotra...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2022-01-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/4590 |
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| author | R. V. Zelchan A. A. Medvedeva O. D. Bragina A. N. Ribina A. I. Ryabova V. I. Chernov E. L. Choynzonov |
| author_facet | R. V. Zelchan A. A. Medvedeva O. D. Bragina A. N. Ribina A. I. Ryabova V. I. Chernov E. L. Choynzonov |
| author_sort | R. V. Zelchan |
| collection | DOAJ |
| description | The review analyzes the global experience in the application of nuclear medicine techniques for diagnosis of tumors and non-tumor pathologies of the brain. The main groups of radiopharmaceuticals currently used for imaging of malignant brain tumors and diagnosis of cognitive impairments and neurotransmitter system disturbances by means of single-photon emission computed tomography and positron emission tomography are described.Modern approaches to the application of methods for radionuclide diagnosis in neuro-oncology and neurology are compared, and the main trends in production of new, more specific radiopharmaceuticals for visualizing brain tumors of various degrees of malignancy and diagnosing non-tumor pathologies of the brain are described. The review discusses the advantages and disadvantages of currently used techniques and radiopharmaceuticals for imaging of central nervous system disorders, depending on the clinical situation and specific diagnostic tasks.In addition, the review presents consolidated recommendations of the leading scientific schools in neuro-oncology on the use of nuclear medicine techniques in patients with brain tumors at the stages of treatment and follow-up. The presented article examines the experience of domestic scientific schools in the development of radiopharmaceuticals for neuro-oncology. The features of the development and use of new radiopharmaceuticals in patients with brain tumors and neurodegenerative diseases are highlighted. The review is based on the analysis of literature included in the Scopus, Web of Science, MedLine, The Cochrane Library, EMBASE, Global Health, and RSCI databases. |
| first_indexed | 2024-04-10T01:05:11Z |
| format | Article |
| id | doaj.art-512429c9d4db478f82738c7ba27ba01d |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:05:11Z |
| publishDate | 2022-01-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-512429c9d4db478f82738c7ba27ba01d2023-03-13T09:58:27ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842022-01-0120413114210.20538/1682-0363-2021-4-131-1422849Modern methods for radionuclide diagnosis of tumors and non-tumor pathologies of the brainR. V. Zelchan0A. A. Medvedeva1O. D. Bragina2A. N. Ribina3A. I. Ryabova4V. I. Chernov5E. L. Choynzonov6Научно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наук; Национальный исследовательский Томский политехнический университет (НИ ТПУ)Научно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наукНаучно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наукНаучно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наук; Национальный исследовательский Томский политехнический университет (НИ ТПУ) 634050, г. Томск, пр. Ленина, 30Научно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наукНаучно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наук; Национальный исследовательский Томский политехнический университет (НИ ТПУ)Научно-исследовательский институт (НИИ) онкологии, Томский национальный исследовательский медицинский центр (НИМЦ) Российской академии наукThe review analyzes the global experience in the application of nuclear medicine techniques for diagnosis of tumors and non-tumor pathologies of the brain. The main groups of radiopharmaceuticals currently used for imaging of malignant brain tumors and diagnosis of cognitive impairments and neurotransmitter system disturbances by means of single-photon emission computed tomography and positron emission tomography are described.Modern approaches to the application of methods for radionuclide diagnosis in neuro-oncology and neurology are compared, and the main trends in production of new, more specific radiopharmaceuticals for visualizing brain tumors of various degrees of malignancy and diagnosing non-tumor pathologies of the brain are described. The review discusses the advantages and disadvantages of currently used techniques and radiopharmaceuticals for imaging of central nervous system disorders, depending on the clinical situation and specific diagnostic tasks.In addition, the review presents consolidated recommendations of the leading scientific schools in neuro-oncology on the use of nuclear medicine techniques in patients with brain tumors at the stages of treatment and follow-up. The presented article examines the experience of domestic scientific schools in the development of radiopharmaceuticals for neuro-oncology. The features of the development and use of new radiopharmaceuticals in patients with brain tumors and neurodegenerative diseases are highlighted. The review is based on the analysis of literature included in the Scopus, Web of Science, MedLine, The Cochrane Library, EMBASE, Global Health, and RSCI databases.https://bulletin.ssmu.ru/jour/article/view/4590ядерная медицинаопухоль головного мозгадеменциярадионуклидная диагностикарадиофармацевтичекий препарат |
| spellingShingle | R. V. Zelchan A. A. Medvedeva O. D. Bragina A. N. Ribina A. I. Ryabova V. I. Chernov E. L. Choynzonov Modern methods for radionuclide diagnosis of tumors and non-tumor pathologies of the brain Бюллетень сибирской медицины ядерная медицина опухоль головного мозга деменция радионуклидная диагностика радиофармацевтичекий препарат |
| title | Modern methods for radionuclide diagnosis of tumors and non-tumor pathologies of the brain |
| title_full | Modern methods for radionuclide diagnosis of tumors and non-tumor pathologies of the brain |
| title_fullStr | Modern methods for radionuclide diagnosis of tumors and non-tumor pathologies of the brain |
| title_full_unstemmed | Modern methods for radionuclide diagnosis of tumors and non-tumor pathologies of the brain |
| title_short | Modern methods for radionuclide diagnosis of tumors and non-tumor pathologies of the brain |
| title_sort | modern methods for radionuclide diagnosis of tumors and non tumor pathologies of the brain |
| topic | ядерная медицина опухоль головного мозга деменция радионуклидная диагностика радиофармацевтичекий препарат |
| url | https://bulletin.ssmu.ru/jour/article/view/4590 |
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