Structural maintenance of chromosomes (SMC) proteins promote homolog-independent recombination repair in meiosis crucial for germ cell genomic stability.
In meiosis, programmed DNA breaks repaired by homologous recombination (HR) can be processed into inter-homolog crossovers that promote the accurate segregation of chromosomes. In general, more programmed DNA double-strand breaks (DSBs) are formed than the number of inter-homolog crossovers, and the...
Main Authors: | Jeremy S Bickel, Liting Chen, Jin Hayward, Szu Ling Yeap, Ashley E Alkers, Raymond C Chan |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-07-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2908675?pdf=render |
Similar Items
-
Chromosome architecture and homologous recombination in meiosis
by: Masaru Ito, et al.
Published: (2023-01-01) -
Caseinolytic mitochondrial matrix peptidase X is essential for homologous chromosome synapsis and recombination during meiosis of male mouse germ cells
by: Hai-Wei Feng, et al.
Published: (2024-01-01) -
Homologous Recombination and Repair Functions Required for Mutagenicity during Yeast Meiosis
by: Liat Morciano, et al.
Published: (2023-10-01) -
Investigating the role of homologous recombination in the maintenance of chromosome stability
by: Graham, E
Published: (2023) -
Teflon promotes chromosomal recruitment of homolog conjunction proteins during Drosophila male meiosis.
by: Zeynep Kabakci, et al.
Published: (2022-10-01)