MiR-132 Regulates Rem Expression in Cardiomyocytes During Long-Term β-Adrenoceptor Agonism

MiR-132 Regulates Rem Expression in Cardiomyocytes During Long-Term β-Adrenoceptor Agonism

Aims: To characterize the effects of long-term β-adrenergic receptor stimulation on Rem protein and mRNA expression in rat heart and possible involvement of miR-132. Methods: Adult rats were treated with isoproterenol (ISO, 150 µg.kg.h-1) for 2 d and Rem, miR-132, and α1c (the principal subunit of C...

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Bibliographic Details
Main Authors: Elba D. Carrillo, Raúl Sampieri, Ascención Hernández, María C. García, Jorge A. Sánchez
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
L-type calcium channel
miR-132
miR-214
Rem
microRNAs
Isoproterenol
α1c Subunit Cav1.2 channel
L-type Ca2+ currents
Ca2+ transients
Online Access:http://www.karger.com/Article/FullText/374059

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