Efficacy of local drug delivery of Achyranthes aspera gel in the management of chronic periodontitis: A clinical study
Context: Periodontitis is an inflammatory disease of microbial origin. Locally delivered antimicrobials reduce subgingival flora. Achyranthes aspera gel has antimicrobial, antioxidant, anti-inflammatory, and immunostimulant effects. Aims: To evaluate the efficacy of local drug delivery of A. aspera...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Journal of Indian Society of Periodontology |
| Subjects: | |
| Online Access: | http://www.jisponline.com/article.asp?issn=0972-124X;year=2017;volume=21;issue=1;spage=46;epage=49;aulast=Boyapati |
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| author | Ramanarayana Boyapati Prathibha Gojja Srikanth Chintalapani Kirankumar Nagubandi Arpita Ramisetti Shyam Sunder Salavadhi |
| author_facet | Ramanarayana Boyapati Prathibha Gojja Srikanth Chintalapani Kirankumar Nagubandi Arpita Ramisetti Shyam Sunder Salavadhi |
| author_sort | Ramanarayana Boyapati |
| collection | DOAJ |
| description | Context: Periodontitis is an inflammatory disease of microbial origin. Locally delivered antimicrobials reduce subgingival flora. Achyranthes aspera gel has antimicrobial, antioxidant, anti-inflammatory, and immunostimulant effects. Aims: To evaluate the efficacy of local drug delivery of A. aspera gel in the management of chronic periodontitis. Materials and Methods: Thirty patients with chronic periodontitis were considered in the study and categorized into two equal groups (Group A: scaling and root planing (SRP) with A. aspera gel, Group B: SRP with placebo gel). Patients were enlisted from the Department of Periodontics, Mamata Dental College and Hospital. The clinical parameters (gingival index, bleeding on probing, probing pocket depth, and clinical attachment level) were recorded at baseline and 3 months. Statistical Analysis Used: All the obtained data were sent for statistical analyses using SPSS version 18. Results: The periodontitis and the Achyranthes were statistically analyzed. A comparison of clinical parameters for test group and control group from baseline to 3 months was done using paired t-test. Intergroup comparison for both the groups was done using independent sample t-test. Conclusions: A. aspera gel when delivered locally along with SRP showed a beneficial effect. A. aspera gel as a non-surgical local drug delivery system proved to be without any side effects in the management of periodontitis. A. aspera gel has strong anti-inflammatory effects in addition to its antioxidant activity. |
| first_indexed | 2024-12-12T07:51:14Z |
| format | Article |
| id | doaj.art-512af2a8f4ae48adad15930dff347cc8 |
| institution | Directory Open Access Journal |
| issn | 0972-124X |
| language | English |
| last_indexed | 2024-12-12T07:51:14Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Society of Periodontology |
| spelling | doaj.art-512af2a8f4ae48adad15930dff347cc82022-12-22T00:32:26ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Periodontology0972-124X2017-01-01211464910.4103/jisp.jisp_130_17Efficacy of local drug delivery of Achyranthes aspera gel in the management of chronic periodontitis: A clinical studyRamanarayana BoyapatiPrathibha GojjaSrikanth ChintalapaniKirankumar NagubandiArpita RamisettiShyam Sunder SalavadhiContext: Periodontitis is an inflammatory disease of microbial origin. Locally delivered antimicrobials reduce subgingival flora. Achyranthes aspera gel has antimicrobial, antioxidant, anti-inflammatory, and immunostimulant effects. Aims: To evaluate the efficacy of local drug delivery of A. aspera gel in the management of chronic periodontitis. Materials and Methods: Thirty patients with chronic periodontitis were considered in the study and categorized into two equal groups (Group A: scaling and root planing (SRP) with A. aspera gel, Group B: SRP with placebo gel). Patients were enlisted from the Department of Periodontics, Mamata Dental College and Hospital. The clinical parameters (gingival index, bleeding on probing, probing pocket depth, and clinical attachment level) were recorded at baseline and 3 months. Statistical Analysis Used: All the obtained data were sent for statistical analyses using SPSS version 18. Results: The periodontitis and the Achyranthes were statistically analyzed. A comparison of clinical parameters for test group and control group from baseline to 3 months was done using paired t-test. Intergroup comparison for both the groups was done using independent sample t-test. Conclusions: A. aspera gel when delivered locally along with SRP showed a beneficial effect. A. aspera gel as a non-surgical local drug delivery system proved to be without any side effects in the management of periodontitis. A. aspera gel has strong anti-inflammatory effects in addition to its antioxidant activity.http://www.jisponline.com/article.asp?issn=0972-124X;year=2017;volume=21;issue=1;spage=46;epage=49;aulast=BoyapatiAchyranthes asperaantioxidantchronic periodontitislocal drug delivery |
| spellingShingle | Ramanarayana Boyapati Prathibha Gojja Srikanth Chintalapani Kirankumar Nagubandi Arpita Ramisetti Shyam Sunder Salavadhi Efficacy of local drug delivery of Achyranthes aspera gel in the management of chronic periodontitis: A clinical study Journal of Indian Society of Periodontology Achyranthes aspera antioxidant chronic periodontitis local drug delivery |
| title | Efficacy of local drug delivery of Achyranthes aspera gel in the management of chronic periodontitis: A clinical study |
| title_full | Efficacy of local drug delivery of Achyranthes aspera gel in the management of chronic periodontitis: A clinical study |
| title_fullStr | Efficacy of local drug delivery of Achyranthes aspera gel in the management of chronic periodontitis: A clinical study |
| title_full_unstemmed | Efficacy of local drug delivery of Achyranthes aspera gel in the management of chronic periodontitis: A clinical study |
| title_short | Efficacy of local drug delivery of Achyranthes aspera gel in the management of chronic periodontitis: A clinical study |
| title_sort | efficacy of local drug delivery of achyranthes aspera gel in the management of chronic periodontitis a clinical study |
| topic | Achyranthes aspera antioxidant chronic periodontitis local drug delivery |
| url | http://www.jisponline.com/article.asp?issn=0972-124X;year=2017;volume=21;issue=1;spage=46;epage=49;aulast=Boyapati |
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