Ameliorative Effects of Neutral Electrolyzed Water on Growth Performance, Biochemical Constituents, and Histopathological Changes in Turkey Poults during Aflatoxicosis
Different in vitro and in silico approaches from our research group have demonstrated that neutral electrolyzed water (NEW) can be used to detoxify aflatoxins. The objective of this investigation was to evaluate the ability of NEW to detoxify B-aflatoxins (AFB1 and AFB2) in contaminated maize and to...
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MDPI AG
2017-03-01
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| Series: | Toxins |
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| Online Access: | http://www.mdpi.com/2072-6651/9/3/104 |
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| author | Denise Gómez-Espinosa Francisco Javier Cervantes-Aguilar Juan Carlos Del Río-García Tania Villarreal-Barajas Alma Vázquez-Durán Abraham Méndez-Albores |
| author_facet | Denise Gómez-Espinosa Francisco Javier Cervantes-Aguilar Juan Carlos Del Río-García Tania Villarreal-Barajas Alma Vázquez-Durán Abraham Méndez-Albores |
| author_sort | Denise Gómez-Espinosa |
| collection | DOAJ |
| description | Different in vitro and in silico approaches from our research group have demonstrated that neutral electrolyzed water (NEW) can be used to detoxify aflatoxins. The objective of this investigation was to evaluate the ability of NEW to detoxify B-aflatoxins (AFB1 and AFB2) in contaminated maize and to confirm detoxification in an in vivo experimental model. Batches of aflatoxin-contaminated maize were detoxified with NEW and mixed in commercial feed. A total of 240 6-day-old female large white Nicholas-700 turkey poults were randomly divided into four treatments of six replicates each (10 turkeys per replicate), which were fed ad libitum for two weeks with the following dietary treatments: (1) control feed containing aflatoxin-free maize (CONTROL); (2) feed containing the aflatoxin-contaminated maize (AF); (3) feed containing the aflatoxin-contaminated maize detoxified with NEW (AF + NEW); and (4) control feed containing aflatoxin-free maize treated with NEW (NEW). Compared to the control groups, turkey poults of the AF group significantly reduced body weight gain and increased feed conversion ratio and mortality rate; whereas turkey poults of the AF + NEW group did not present significant differences on productive parameters. In addition, alterations in serum biochemical constituents, enzyme activities, relative organ weight, gross morphological changes and histopathological studies were significantly mitigated by the aflatoxin-detoxification procedure. From these results, it is concluded that the treatment of aflatoxin-contaminated maize with NEW provided reasonable protection against the effects caused by aflatoxins in young turkey poults. |
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| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-04-11T21:39:19Z |
| publishDate | 2017-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-512b3b3ab6874911bc06d17a378da7e72022-12-22T04:01:39ZengMDPI AGToxins2072-66512017-03-019310410.3390/toxins9030104toxins9030104Ameliorative Effects of Neutral Electrolyzed Water on Growth Performance, Biochemical Constituents, and Histopathological Changes in Turkey Poults during AflatoxicosisDenise Gómez-Espinosa0Francisco Javier Cervantes-Aguilar1Juan Carlos Del Río-García2Tania Villarreal-Barajas3Alma Vázquez-Durán4Abraham Méndez-Albores5National Autonomous University of Mexico-Superior Studies Faculty at Cuautitlan (UNAM-FESC), Master in Animal Production and Health Sciences, Cuautitlan Izcalli 54714, MexicoNational Autonomous University of Mexico-Superior Studies Faculty at Cuautitlan (UNAM-FESC), Veterinary Medicine and Animal Husbandry, Department of Biological and Livestock Sciences, Cuautitlan Izcalli 54714, MexicoNational Autonomous University of Mexico-Superior Studies Faculty at Cuautitlan (UNAM-FESC), Campus 4, Multidisciplinary Research Unit L14 (Food, Mycotoxins and Mycotoxicosis), Cuautitlan Izcalli 54714, MexicoEsteripharma SA de CV, Atlacomulco 50450, MexicoNational Autonomous University of Mexico-Superior Studies Faculty at Cuautitlan (UNAM-FESC), Campus 4, Multidisciplinary Research Unit L14 (Food, Mycotoxins and Mycotoxicosis), Cuautitlan Izcalli 54714, MexicoNational Autonomous University of Mexico-Superior Studies Faculty at Cuautitlan (UNAM-FESC), Campus 4, Multidisciplinary Research Unit L14 (Food, Mycotoxins and Mycotoxicosis), Cuautitlan Izcalli 54714, MexicoDifferent in vitro and in silico approaches from our research group have demonstrated that neutral electrolyzed water (NEW) can be used to detoxify aflatoxins. The objective of this investigation was to evaluate the ability of NEW to detoxify B-aflatoxins (AFB1 and AFB2) in contaminated maize and to confirm detoxification in an in vivo experimental model. Batches of aflatoxin-contaminated maize were detoxified with NEW and mixed in commercial feed. A total of 240 6-day-old female large white Nicholas-700 turkey poults were randomly divided into four treatments of six replicates each (10 turkeys per replicate), which were fed ad libitum for two weeks with the following dietary treatments: (1) control feed containing aflatoxin-free maize (CONTROL); (2) feed containing the aflatoxin-contaminated maize (AF); (3) feed containing the aflatoxin-contaminated maize detoxified with NEW (AF + NEW); and (4) control feed containing aflatoxin-free maize treated with NEW (NEW). Compared to the control groups, turkey poults of the AF group significantly reduced body weight gain and increased feed conversion ratio and mortality rate; whereas turkey poults of the AF + NEW group did not present significant differences on productive parameters. In addition, alterations in serum biochemical constituents, enzyme activities, relative organ weight, gross morphological changes and histopathological studies were significantly mitigated by the aflatoxin-detoxification procedure. From these results, it is concluded that the treatment of aflatoxin-contaminated maize with NEW provided reasonable protection against the effects caused by aflatoxins in young turkey poults.http://www.mdpi.com/2072-6651/9/3/104maizeaflatoxinsneutral electrolyzed waterdetoxificationturkey |
| spellingShingle | Denise Gómez-Espinosa Francisco Javier Cervantes-Aguilar Juan Carlos Del Río-García Tania Villarreal-Barajas Alma Vázquez-Durán Abraham Méndez-Albores Ameliorative Effects of Neutral Electrolyzed Water on Growth Performance, Biochemical Constituents, and Histopathological Changes in Turkey Poults during Aflatoxicosis Toxins maize aflatoxins neutral electrolyzed water detoxification turkey |
| title | Ameliorative Effects of Neutral Electrolyzed Water on Growth Performance, Biochemical Constituents, and Histopathological Changes in Turkey Poults during Aflatoxicosis |
| title_full | Ameliorative Effects of Neutral Electrolyzed Water on Growth Performance, Biochemical Constituents, and Histopathological Changes in Turkey Poults during Aflatoxicosis |
| title_fullStr | Ameliorative Effects of Neutral Electrolyzed Water on Growth Performance, Biochemical Constituents, and Histopathological Changes in Turkey Poults during Aflatoxicosis |
| title_full_unstemmed | Ameliorative Effects of Neutral Electrolyzed Water on Growth Performance, Biochemical Constituents, and Histopathological Changes in Turkey Poults during Aflatoxicosis |
| title_short | Ameliorative Effects of Neutral Electrolyzed Water on Growth Performance, Biochemical Constituents, and Histopathological Changes in Turkey Poults during Aflatoxicosis |
| title_sort | ameliorative effects of neutral electrolyzed water on growth performance biochemical constituents and histopathological changes in turkey poults during aflatoxicosis |
| topic | maize aflatoxins neutral electrolyzed water detoxification turkey |
| url | http://www.mdpi.com/2072-6651/9/3/104 |
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