The association between NOTCH3 expression and the clinical outcome in the urothelial bladder cancer patients

The association between NOTCH3 expression and the clinical outcome in the urothelial bladder cancer patients

Disrupted NOTCH activity is a driving event in urothelial bladder cancer (UBC). After activation by hypoxia, the NOTCH3 receptor participates in tumor cell proliferation, acquisition of the epithelial-mesenchymal transition phenotype, and angiogenesis. The aim was to analyze the association of NOTCH...

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Bibliographic Details
Main Authors: Ana Ristic Petrovic, Dragana Stokanović, Slavica Stojnev, Milena Potić Floranović, Miljan Krstić, Ivana Djordjević, Aleksandar Skakić, Ljubinka Janković Veličković
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2022-07-01
Series:Biomolecules & Biomedicine
Subjects:
bladder cancer
clinical outcome
NOTCH pathway
NOTCH3
immunohistochemistry
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/6767

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