Surface Display Technology for Biosensor Applications: A Review
Surface display is a recombinant technology that expresses target proteins on cell membranes and can be applied to almost all types of biological entities from viruses to mammalian cells. This technique has been used for various biotechnical and biomedical applications such as drug screening, biocat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-05-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/20/10/2775 |
| _version_ | 1797568091537801216 |
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| author | Min Park |
| author_facet | Min Park |
| author_sort | Min Park |
| collection | DOAJ |
| description | Surface display is a recombinant technology that expresses target proteins on cell membranes and can be applied to almost all types of biological entities from viruses to mammalian cells. This technique has been used for various biotechnical and biomedical applications such as drug screening, biocatalysts, library screening, quantitative assays, and biosensors. In this review, the use of surface display technology in biosensor applications is discussed. In detail, phage display, bacterial surface display of Gram-negative and Gram-positive bacteria, and eukaryotic yeast cell surface display systems are presented. The review describes the advantages of surface display systems for biosensor applications and summarizes the applications of surface displays to biosensors. |
| first_indexed | 2024-03-10T19:51:26Z |
| format | Article |
| id | doaj.art-512e58cd1ed64dcc892d9ad8bfb0fbb4 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T19:51:26Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-512e58cd1ed64dcc892d9ad8bfb0fbb42023-11-20T00:21:30ZengMDPI AGSensors1424-82202020-05-012010277510.3390/s20102775Surface Display Technology for Biosensor Applications: A ReviewMin Park0Major in Materials Science and Engineering, Hallym University, Chuncheon, Gangwon-do 24252, KoreaSurface display is a recombinant technology that expresses target proteins on cell membranes and can be applied to almost all types of biological entities from viruses to mammalian cells. This technique has been used for various biotechnical and biomedical applications such as drug screening, biocatalysts, library screening, quantitative assays, and biosensors. In this review, the use of surface display technology in biosensor applications is discussed. In detail, phage display, bacterial surface display of Gram-negative and Gram-positive bacteria, and eukaryotic yeast cell surface display systems are presented. The review describes the advantages of surface display systems for biosensor applications and summarizes the applications of surface displays to biosensors.https://www.mdpi.com/1424-8220/20/10/2775biosensorssurface displaymolecular recognition layermolecular displayphage displaybacterial surface display |
| spellingShingle | Min Park Surface Display Technology for Biosensor Applications: A Review Sensors biosensors surface display molecular recognition layer molecular display phage display bacterial surface display |
| title | Surface Display Technology for Biosensor Applications: A Review |
| title_full | Surface Display Technology for Biosensor Applications: A Review |
| title_fullStr | Surface Display Technology for Biosensor Applications: A Review |
| title_full_unstemmed | Surface Display Technology for Biosensor Applications: A Review |
| title_short | Surface Display Technology for Biosensor Applications: A Review |
| title_sort | surface display technology for biosensor applications a review |
| topic | biosensors surface display molecular recognition layer molecular display phage display bacterial surface display |
| url | https://www.mdpi.com/1424-8220/20/10/2775 |
| work_keys_str_mv | AT minpark surfacedisplaytechnologyforbiosensorapplicationsareview |