Use of a conformational switching aptamer for rapid and specific ex vivo identification of central nervous system lymphoma in a xenograft model.

Use of a conformational switching aptamer for rapid and specific ex vivo identification of central nervous system lymphoma in a xenograft model.

Improved tools for providing specific intraoperative diagnoses could improve patient care. In neurosurgery, intraoperatively differentiating non-operative lesions such as CNS B-cell lymphoma from operative lesions can be challenging, often necessitating immunohistochemical (IHC) procedures which req...

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Bibliographic Details
Main Authors: Joseph F Georges, Xiaowei Liu, Jennifer Eschbacher, Joshua Nichols, Michael A Mooney, Anna Joy, Robert F Spetzler, Burt G Feuerstein, Mark C Preul, Trent Anderson, Hao Yan, Peter Nakaji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4398547?pdf=render

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