Megaduodenum in a patient with acromegaly
Introduction: Acromegaly is associated with enlargement of all organs including the gastro intestinal system. However, there are no previous reports of occurrence of megaduodenum in patients with acromegaly. Discussion: We present the case of a 47 year old male who was diagnosed to have acromegaly 1...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=8;spage=324;epage=325;aulast=George |
| _version_ | 1818534794320936960 |
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| author | Belinda George D Vinay J Moolechery V Mathew R Anantharaman V Ayyar G Bantwal |
| author_facet | Belinda George D Vinay J Moolechery V Mathew R Anantharaman V Ayyar G Bantwal |
| author_sort | Belinda George |
| collection | DOAJ |
| description | Introduction: Acromegaly is associated with enlargement of all organs including the gastro intestinal system. However, there are no previous reports of occurrence of megaduodenum in patients with acromegaly. Discussion: We present the case of a 47 year old male who was diagnosed to have acromegaly 13 years ago and had undergone transsphenoidal surgery twice with incomplete removal of the pituitary macro-adenoma and received radiotherapy following the second surgery. Patient has been on replacement therapy for hypocortisolism, hypothyroidism and hypogonadism since 10 years. Post glucose growth hormone level continued to remain unsuppressed; however, patient never received any medical therapy for acromegaly. He was evaluated with esophago-gastro-duodenoscopy for recurrent abdominal pain and distension, which showed an elongated and tortuous megaduodenum. These findings were verified with a barium study which revealed dilated stomach, first and second part of duodenum with no evidence of a distal obstruction. Conclusions: We report this finding in view of the rare association. |
| first_indexed | 2024-12-11T18:16:13Z |
| format | Article |
| id | doaj.art-5137442cdf2944b1b0f9f5f30d3498d7 |
| institution | Directory Open Access Journal |
| issn | 2230-8210 2230-9500 |
| language | English |
| last_indexed | 2024-12-11T18:16:13Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-5137442cdf2944b1b0f9f5f30d3498d72022-12-22T00:55:24ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102230-95002012-01-0116832432510.4103/2230-8210.104076Megaduodenum in a patient with acromegalyBelinda GeorgeD VinayJ MoolecheryV MathewR AnantharamanV AyyarG BantwalIntroduction: Acromegaly is associated with enlargement of all organs including the gastro intestinal system. However, there are no previous reports of occurrence of megaduodenum in patients with acromegaly. Discussion: We present the case of a 47 year old male who was diagnosed to have acromegaly 13 years ago and had undergone transsphenoidal surgery twice with incomplete removal of the pituitary macro-adenoma and received radiotherapy following the second surgery. Patient has been on replacement therapy for hypocortisolism, hypothyroidism and hypogonadism since 10 years. Post glucose growth hormone level continued to remain unsuppressed; however, patient never received any medical therapy for acromegaly. He was evaluated with esophago-gastro-duodenoscopy for recurrent abdominal pain and distension, which showed an elongated and tortuous megaduodenum. These findings were verified with a barium study which revealed dilated stomach, first and second part of duodenum with no evidence of a distal obstruction. Conclusions: We report this finding in view of the rare association.http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=8;spage=324;epage=325;aulast=GeorgeAcromegalymegaduodenumduodenum |
| spellingShingle | Belinda George D Vinay J Moolechery V Mathew R Anantharaman V Ayyar G Bantwal Megaduodenum in a patient with acromegaly Indian Journal of Endocrinology and Metabolism Acromegaly megaduodenum duodenum |
| title | Megaduodenum in a patient with acromegaly |
| title_full | Megaduodenum in a patient with acromegaly |
| title_fullStr | Megaduodenum in a patient with acromegaly |
| title_full_unstemmed | Megaduodenum in a patient with acromegaly |
| title_short | Megaduodenum in a patient with acromegaly |
| title_sort | megaduodenum in a patient with acromegaly |
| topic | Acromegaly megaduodenum duodenum |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=8;spage=324;epage=325;aulast=George |
| work_keys_str_mv | AT belindageorge megaduodenuminapatientwithacromegaly AT dvinay megaduodenuminapatientwithacromegaly AT jmoolechery megaduodenuminapatientwithacromegaly AT vmathew megaduodenuminapatientwithacromegaly AT ranantharaman megaduodenuminapatientwithacromegaly AT vayyar megaduodenuminapatientwithacromegaly AT gbantwal megaduodenuminapatientwithacromegaly |